20797-48-2

Usage

Uses

Used in Chemical Synthesis:
4-Chloro-3-nitrocinnamic acid is used as a key intermediate in the synthesis of various organic compounds and pharmaceuticals. Its unique structure allows it to participate in a range of chemical reactions, making it a valuable building block for the development of new molecules with potential applications in various industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Chloro-3-nitrocinnamic acid is used as a starting material for the synthesis of drug candidates. Its chemical properties enable the creation of new compounds with potential therapeutic effects, contributing to the discovery and development of novel medications.
Used in Agrochemical Industry:
4-Chloro-3-nitrocinnamic acid is also utilized in the agrochemical industry for the synthesis of active ingredients in pesticides and herbicides. Its reactivity and structural features make it suitable for the development of effective crop protection products.
Used in Dye and Pigment Industry:
In the dye and pigment industry, 4-Chloro-3-nitrocinnamic acid is employed as a precursor for the production of various dyes and pigments. Its yellow crystalline nature and chemical properties contribute to the creation of colorants with specific characteristics, suitable for different applications such as textiles, plastics, and printing inks.

InChI:InChI=1/C9H6ClNO4/c10-7-3-1-6(2-4-9(12)13)5-8(7)11(14)15/h1-5H,(H,12,13)/p-1/b4-2+

Upstream product

• 20797-44-8 β-(4-Chlor-3-nitro-phenyl)-α-chlor-propionsaeure 
• 30565-73-2 α,p-Dichlor-m-nitro-hydrozimtsaeure-methylester 
• 1615-02-7 3-(4-chlorophenyl)prop-2-enoic acid 
• 7697-37-2 nitric acid 
• 2033-24-1 cycl-isopropylidene malonate 
• 16588-34-4 4-chloro-3-nitro-benzaldehyde 
• 141-82-2 malonic acid 
• 55912-20-4 4-chloro-3-nitrobenzyl alcohol 

Downstream Products

• 780-12-1 4-chloro-3,β-dinitro-styrene 
• 1151562-56-9 3-(4-(2-(diethylamino)ethylthio)-3-nitrophenyl)acrylic acid 
• 1262014-52-7 C₉H₈ClNO₂ 
• 42174-78-7 (E)-ethyl 3-(4-chloro-3-nitrophenyl)acrylate 
• 133100-23-9 3-(4-chloro-3-nitrophenyl)propionic acid 
• 301179-69-1 1-chloro-2-nitro-4-((E)-((4-acetylpiperazin-1-yl)carbonyl)ethenyl)benzene 
• 280752-92-3 3-(4-chloro-3-nitro-phenyl)-N-[3-(2-oxo-pyrrolidin-1-yl)-propyl]-acrylamide 
• 280752-62-7 3-[4-(2-isopropylphenylsulfanyl)-3-nitrophenyl]acrylic acid 
• 42564-43-2 C₁₀H₁₀N₂O₄ 
• 849059-63-8 3-[3-nitro-4-(hydroxypropylamine)-phenyl]-acrylic acid 
• 877065-30-0 3-(4-chloro-3-nitrophenyl)acrylic acid methyl ester 
• 849059-79-6 3-[4-(3-dimethylamino-2,2-dimethyl-propylamino)-3-nitro-phenyl]-acrylic acid 
• 1145979-12-9 C₁₆H₂₁N₃O₄ 
• 51794-06-0 4-Amino-3-nitrocinnamic acid 

Relevant academic research and scientific papers

Synthesis and characterization of two novel biological-based nano organo solid acids with urea moiety and their catalytic applications in the synthesis of 4,4′-(arylmethylene)bis(1H-pyrazol-5-ol), coumarin-3-carboxylic acid and cinnamic acid derivatives under mild and green conditions

2-Carbamoylhydrazine-1-sulfonic acid and carbamoylsulfamic acid as novel, mild and biological-based nano organocatalysts with urea moiety were designed, synthesized and fully characterized by FT-IR, 1H NMR, 13C NMR, mass spectrometry, elemental analysis, thermal gravimetric, derivative thermal gravimetric, X-ray diffraction patterns, scanning electron microscopy, transmission electron microscopy, energy-dispersive X-ray spectroscopy, atomic force microscopy and UV/Vis analysis. The catalytic applications of 2-carbamoylhydrazine-1-sulfonic acid and carbamoylsulfamic acid were studied in the synthesis of 4,4′-(arylmethylene)bis(1H-pyrazol-5-ol), coumarin-3-carboxylic acid and cinnamic acid derivatives via the condensation reaction between several aromatic aldehydes and 1-phenyl-3-methylpyrazol-5-one (synthesis of 4,4′-(arylmethylene)bis(1H-pyrazol-5-ols)), the Knoevenagel condensation of Meldrum's acid with salicylaldehyde derivatives (synthesis of coumarin-3-carboxylic acids) and the condensation of Meldrum's acid with aromatic aldehydes (synthesis of cinnamic acids) under mild and solvent-free conditions. In the presented studies, some products were formed and reported for the first time. The described nano organo solid acids have potential in industry.

Competitive formation of β-amino acids, propenoic, and ylidenemalonic acids by the Rodionov reaction from malonic acid, aldehydes, and ammonium acetate in alcoholic medium

The Rodionov reaction of 49 available aliphatic and aromatic aldehydes with malonic acid and ammonium acetate in alcoholic medium, resulting in formation of β-amino acids, propenoic, and ylidenemalonic acids, was studied. Certain regioselectivity regularities of the reaction were revealed. Among the variety of ketones studied, cyclohexanone is the only whose reaction yields a β-amino acid. Unusual dehydrofluorination of 6-chloro-2-fluorocinnamic acid under the Rodionov reaction was discovered. 2005 Pleiades Publishing, Inc.