349555-96-0

Upstream product

• 100-39-0 benzyl bromide 
• 305838-42-0 (2S,3R)-1-(tert-butyldimethylsilanyloxy)-2-dibenzylamino-5-[1,3]dioxolan-2-yl-pentan-3-ol 
• 125654-82-2 (S)-3-(tert-Butyl-dimethyl-silanyloxy)-2-dibenzylamino-propionaldehyde 
• 18742-02-4 2-bromo-2-(2-ethyl)dioxolane 

Downstream Products

• 349556-02-1 (4R,5S)-6-(tert-butyldimethylsilanyloxy)-4-benzyloxy-5-dibenzylaminohexanal 
• 349556-03-2 (2S,3R)-1-(tert-butyldimethylsilanyloxy)-3-benzyloxy-2-dibenzylaminooctadecane-1,6-diol 
• 349556-00-9 (2S,3R)-1-(tert-butyldimethylsilanyloxy)-3-benzyloxy-2-dibenzylamino-6-oxooctadecan-6-one 
• 849428-89-3 (2S,3R,6S)-(3-benzyloxy-6-dodecylpiperidin-2-yl)methanol 
• 14058-54-9 (-)-deoxoprosophylline 
• 849428-90-6 (2S,3R)-3-benzyloxy-2-dibenzylamino[1,3]dioxolan-6-yl-octadecan-1-ol 
• 849428-92-8 [(1S,2R)-2-Benzyloxy-4-(2-dodecyl-[1,3]dioxolan-2-yl)-1-hydroxymethyl-butyl]-carbamic acid benzyl ester 
• 849428-93-9 ((1S,2R)-2-Benzyloxy-1-hydroxymethyl-5-oxo-heptadecyl)-carbamic acid benzyl ester 
• 849428-94-0 (2S,3R,6R)-3-Benzyloxy-6-dodecyl-2-hydroxymethyl-piperidine-1-carboxylic acid benzyl ester 
• 849428-91-7 (2S,3R)-2-amino-3-benzyloxy[1,3]dioxolan-6-yl-octadecan-1-ol 
• 349555-97-1 (4R,5S)-4-Benzyloxy-5-dibenzylamino-6-hydroxy-hexanal 

Relevant academic research and scientific papers

A short synthesis of (-)-deoxoprosophylline

Syntheses of (-)-deoxoprosophylline from chiral L-N,N-dibenzylserine (TBDMS) aldehyde is reported. A highly diastereoselective nucleophilic addition of Buechi's Grignard reagent to chiral serinal followed by an intramolecular reductive amination of ω-oxo

Asymmetric total synthesis of (-)-deoxoprosophylline

Asymmetric syntheses of (-)-deoxoprosophylline from chiral L-N,N-dibenzyl serine (TBDMS) aldehyde is reported. A highly diastereoselective intramolecular reductive amination of ω-oxo amino diol is a key step of the present synthesis.