849435-67-2

Upstream product

• 97-02-9 2,4-Dinitroanilin 
• 623-66-5 octanoic acid anhydride 
• 99723-34-9 octanoic acid (2,4-dinitro-phenyl)-amide 

Relevant academic research and scientific papers

Baker's yeast-mediated regioselective reduction of 2,4-dinitroacylanilines: Synthesis of 2-substituted 6-nitrobenzimidazoles

Several 2,4-dinitro-N-acylanilines were regioselectively reduced at the C-2 position by baker's yeast in slightly basic media (pH = 7.5) to afford 2-amino-4-nitroacylanilines, which were then cyclized under acidic conditions to the corresponding 2-substituted-6-nitrobenzimidazoles. The benzimidazoles thus obtained can be employed as precursors for bioactive derivatives.