84946-00-9

Usage

InChI:InChI=1/C15H26Cl2N4/c1-3-5-7-9-11-21(12-10-8-6-4-2)15-19-13(16)18-14(17)20-15/h3-12H2,1-2H3

Upstream product

• 108-77-0 1,3,5-trichloro-2,4,6-triazine 
• 143-16-8 dihexylamine 

Downstream Products

• 255864-82-5 2-dihexylamino-4,6-bis(3-N-ethoxycarbonylaminomethyl)benzylamino-s-triazine 
• 1428262-17-2 C₂₁H₃₉ClN₄O 
• 255864-83-6 2-dihexylamino-4,6-bis(3-aminomethyl)benzylamino-s-triazine 

Relevant academic research and scientific papers

Synthesis and properties of x-type alkyl sulfonate gemini surfactants derived from cyanuric chloride

A series of X-type alkyl sulfonate Gemini surfactants (XCn, n = 6, 8, 10) was synthesized by a simple method. The chemical structures of the prepared compounds were confirmed by 1H NMR, 13C NMR, ESI-MS and Elementary analysis. The surface activity and thermodynamic properties of micellization of the X-type alkyl sulfonate Gemini surfactants were compared with sodium dodecylsulfate by means of surface tension. The properties of XCn are superior to those of SDS such as the λCMC and CMC of XC10 are 26.3 mN/m and 0.2 mmol/L respectively. The adsorption isotherms for XCn were established by fitting the pre-CMC surface tension data with a quadratic function. The thermodynamic parameters of micellization (δG°m, δH°m , δS°m) derived from electrical conductivity indicate that the micellization of XCn is entropy-driven. AOCS 2011.

Induction of the columnar phase of unconventional dendrimers by breaking the C2 symmetry of molecules

Two triazine-based unconventional dendrimers were prepared and characterized by 1H and 13C NMR spectroscopy, mass spectrometry, and elemental analysis. Differential scanning calorimetry, polarizing microscopy, and powder XRD studies showed that these dendrimers display columnar liquid-crystalline phases during thermal treatment. This is ascribable to breaking of their C2 symmetry. The molecular conformations of prepared dendrimers were obtained by computer simulation with the MM3 model of the CaChe program in the gas phase. The simulation showed that the conformations of the prepared dendrimers are rather flat and disfavor formation of the LC phase. However, due to C2-symmetry breaking, the prepared dendrimers have structural isomers in the solid state and thus show the desired columnar phases. This new strategy should be applicable to other types of unconventional dendrimers with rigid frameworks. Broken symmetry: Unconventional triazine-based dendrimers (see figure) were prepared and, according to studies by differential scanning calorimetry, polarizing microscopy, and powder XRD, they display columnar liquid-crystalline (LC) phases. Simulations indicate that the conformations of the dendrimers are rather flat and disfavor formation of the LC phase. However, due to C 2-symmetry breaking, they have structural isomers in the solid state and thus show the desired columnar phases. Copyright

Compounds which inhibit leukocyte adhesion mediated by VLA-4

Disclosed are compounds which bind VLA-4. Certain of these compounds also inhibit leukocyte adhesion and, in particular, leukocyte adhesion mediated by VLA-4. Such compounds are useful in the treatment of inflammatory diseases in a mammalian patient, e.g., human, such as asthma, Alzheimer's disease, atherosclerosis, AIDS dementia, diabetes, inflammatory bowel disease, rheumatoid arthritis, tissue transplantation, tumor metastasis and myocardial ischemia. The compounds can also be administered for the treatment of inflammatory brain diseases such as multiple sclerosis.

Functionalized flavin receptors. Regulation of redox properties of 6- Azaflavin via hydrogen bondings with melamine derivatives bearing guanidinium ion(s) in organic solvents

Melamine derivatives bearing guanidinium ion(s) were synthesized as a flavin receptor using hydrogen bonds. The receptors bind 6-aza-10- dodecylisoalloxazine (6-azaflavin, 6-AzaFl) quite strongly via five or seven hydrogen bonds in CHCl3 or CHCl3-MeCN. Redox potentials of 6-AzaFl were considerably affected by hydrogen bondings of the receptors (positive shift: ΔE( 1/2 ) = 220-317 mV). Anionic semiquinone radical of 6-AzaFl was found to be stabilized by hydrogen bondings with a melamine derivative bearing an N- phenylguanidinium ion or two guanidinium ions. Effects of the hydrogen bondings on the oxidation activity of 6-AzaFl were kinetically investigated for the oxidation of N-benzyl-1,4-dihydronicotinamide (BNAH) and PhSH in CHCl3-MeCN under anaerobic conditions. It was found that the N(1)-hydrogen bonding facilitates a slight BNAH oxidation (3 - 104-fold).