84956-00-3Relevant academic research and scientific papers
REACTION OF TRIMETHYLSILYL ENOL ETHERS WITH ISOQUINOLINIUM SALTS. A FACILE SYNTHESIS OF ETHYL 1-(2-OXOALKYL)-1,2-DIHYDROISOQUINOLINE-2-CARBOXYLATES AND THEIR CYCLIZATION
Wada, Makoto,Nakatani, Masayuki,Akiba, Kin-ya
, p. 39 - 42 (1983)
An efficient method is described for the synthesis of ethyl 1-(2-oxoalkyl)-1,2-dihydroisoquinoline-2-carboxylates by C-C bond formation between 2-ethoxycarbonylisoquinolinium chloride and trimethylsilyl enol ethers.The products were treated with a few bases to afford the corresponding pyridoisoquinoline derivatives.
