Chemistry Letters p. 39 - 42 (1983)
Update date:2022-08-04
Topics:
Wada, Makoto
Nakatani, Masayuki
Akiba, Kin-ya
An efficient method is described for the synthesis of ethyl 1-(2-oxoalkyl)-1,2-dihydroisoquinoline-2-carboxylates by C-C bond formation between 2-ethoxycarbonylisoquinolinium chloride and trimethylsilyl enol ethers.The products were treated with a few bases to afford the corresponding pyrido<2,1-a>isoquinoline derivatives.
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Doi:10.1055/s-1982-30024
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