849767-19-7

Basic information

• Product Name: tert-butyl 4-hydroxy-3-(hydroxymethyl)piperidine-1-carboxylate
• Synonyms: tert-butyl 4-hydroxy-3-(hydroxymethyl)piperidine-1-carboxylate
• CAS NO: 849767-19-7
• Molecular Formula: C11H21NO4
• Molecular Weight: 231.28874
• Mol File: 849767-19-7.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: tert-butyl 4-hydroxy-3-(hydroxymethyl)piperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-hydroxy-3-(hydroxymethyl)piperidine-1-carboxylate(849767-19-7)
• EPA Substance Registry System: tert-butyl 4-hydroxy-3-(hydroxymethyl)piperidine-1-carboxylate(849767-19-7)

Safety Data

• Hazardous Substances Data: 849767-19-7(Hazardous Substances Data)

Usage

Description

Tert-butyl 4-hydroxy-3-(hydroxymethyl)piperidine-1-carboxylate is a chemical compound with the molecular formula C13H23NO4. It is a derivative of piperidine, characterized by its white solid form and solubility in organic solvents. tert-butyl 4-hydroxy-3-(hydroxymethyl)piperidine-1-carboxylate is stable under normal conditions and is primarily recognized for its role as a pharmaceutical intermediate in the synthesis of various medications.

Uses

Used in Pharmaceutical Industry:
Tert-butyl 4-hydroxy-3-(hydroxymethyl)piperidine-1-carboxylate is utilized as a pharmaceutical intermediate for its ability to modify the properties of certain drugs. It plays a crucial role in enhancing the stability and bioavailability of medications, thereby improving their overall effectiveness and safety.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, tert-butyl 4-hydroxy-3-(hydroxymethyl)piperidine-1-carboxylate is employed for the development of new pharmaceutical compounds. Its unique structure and properties make it a valuable component in the creation of innovative and potentially life-saving medications.

Upstream product

• 98977-34-5 1-tert-butyl 3-ethyl 4-oxopiperidine-1,3-dicarboxylate 
• 1454-53-1 ethyl 1-benzyl-4-oxopiperidine-3-carboxylate hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 71486-53-8 methyl 4-oxo-3-piperidinecarboxylate hydrochloride 
• 161491-24-3 methyl 1-tert-butoxycarbonyl-4-oxo-3-piperidinecarboxylate 

Downstream Products

• 1331775-94-0 4-[6-butyl-5-(4-cyclohexyloxyphenyl)pyridazin-3-yloxy]-3-methoxymethoxymethylpiperidine-1-carboxylic acid tert-butyl ester 
• 849767-21-1 tert-butyl 3-[[tert-butyl(dimethyl)silyl]oxymethyl]-4-oxo-piperidine-1-carboxylate 

Relevant articles and documents

CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF

Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of chemokine receptor activity.

FUSED PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS

The invention relates to fused piperidine amides useful as inhibitors of ion channels for the treatment of pain. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

PHENYL-HETEROARYL DERIVATIVES AND METHODS OF USE THEREOF

The present invention provides phenyl-heteroaryl derivatives of Formula (I) and pharmaceutically acceptable salts thereof. These compounds are useful in the treatment of RAGE-mediated diseases such as Alzheimer's Disease. The present invention further relates to methods for the preparation of compounds of Formula (I) and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising such compounds, and the use of such compounds and/or pharmaceutical compositions in treating RAGE-mediated diseases.