849925-83-3Relevant academic research and scientific papers
Synthesis and evaluation of pyrazolidine derivatives as dipeptidyl peptidase IV (DP-IV) inhibitors
Ahn, Jin Hee,Kim, Jin Ah,Kim, Hye-Min,Kwon, Hyuk-Man,Huh, Sun-Chul,Rhee, Sang Dal,Kim, Kwang Rok,Yang, Sung-Don,Park, Sung-Dae,Lee, Jae Mok,Kim, Sung Soo,Cheon, Hyae Gyeong
, p. 1337 - 1340 (2007/10/03)
A new series of pyrazolidine derivatives was synthesized and evaluated for their ability to inhibit dipeptidyl peptidase IV (DP-IV). Compound 9i was the most active in this series, exhibited IC50 value of 1.56 μM and ED50 value of 80
