849943-91-5Relevant academic research and scientific papers
Fluoride Migration Catalysis Enables Simple, Stereoselective, and Iterative Glycosylation
Malakar, Tanmay,Martin, Joshua L.,Montgomery, John,Sati, Girish C.,Xu, Yishu,Zimmerman, Paul M.
supporting information, p. 7235 - 7242 (2020/05/19)
Challenges in the assembly of glycosidic bonds in oligosaccharides and glycoconjugates pose a bottleneck in enabling the remarkable promise of advances in the glycosciences. Here, we report a strategy that applies unique features of highly electrophilic b
METHODS FOR GLYCOSYLATION
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Paragraph 0056; 0137; 0185-0186, (2020/11/30)
Provided herein are methods of glycosylation in the formation of disaccharides, trisaccharides, and oligosaccharides using fluoroglycosides, silyl ether glycosides and a triaryl borane catalyst.
Direct O-glycosidation of resin bound thioglycosides
Nguyen, Son Hong,Trotta, Adam H.,Cao, John,Straub, Timothy J.,Bennett, Clay S.
supporting information; experimental part, p. 2373 - 2376 (2012/04/11)
The application of the safety-catch linker concept to solid-phase glycoconjugate synthesis is described. The process allows for direct conjugation of resin bound glycans to complex aglycones during cleavage. Large excesses of either coupling partner are not required, and even very hindered alcohols serve as acceptors in the reaction. The Royal Society of Chemistry 2012.
Glycal scavenging in the synthesis of disaccharides using mannosyl iodide donors
Lam, Son N.,Gervay-Hague, Jacquelyn
, p. 2387 - 2390 (2007/10/03)
(Chemical Equation Presented) High mannose glycans composed of α (1→2) and α (1→6) branched sugars are important components of the HIV-associated envelope glycoprotein, gp120. These substructures can be efficiently prepared in solution from glycosyl iodid
