850008-77-4Relevant academic research and scientific papers
Pd(0)-Catalyzed Direct Inter- And Intramolecular C-H Functionalization of 4-Carboxyimidazoles
Frippiat, Steven,Peresson, Antoine,Perse, Thibaut,Ramondenc, Yvan,Schneider, Cédric,Querolle, Olivier,Angibaud, Patrick,Poncelet, Virginie,Meerpoel, Lieven,Levacher, Vincent,Bischoff, Laurent,Baudequin, Christine,Hoarau, Christophe
, p. 1015 - 1021 (2020/06/17)
The palladium-catalyzed arylation and alkenylation of N -substituted methyl imidazole-4-carboxylates are described through inter- and intramolecular pathways. Both direct C2-H and C5-H arylation and alkenylation proceed under Pd(0)/Cu(I) cooperative catal
Imidazole derivatives as PDE10A enzyme inhibitors
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Page/Page column 10, (2012/06/01)
This invention is directed to compounds, which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The pr
Synthetic applications of aryl radical building blocks for cyclisation onto azoles
Allin, Steven M.,Bowman, W. Russell,Elsegood, Mark R.J.,McKee, Vickie,Karim, Rehana,Rahman, Shahzad S.
, p. 2689 - 2696 (2007/10/03)
2-(2-Bromophenyl)ethyl groups have been used as building blocks in radical cyclisation reactions onto azoles to synthesise tri- and tetra-cyclic heterocycles. 2-(2-Bromophenyl)ethyl methanesulfonate was used to alkylate azoles (imidazoles, pyrroles, indol
