850011-53-9Relevant articles and documents
A new synthesis of β-amino acids by use of ketene diethyl acetal as enolate equivalent
Rossen, Kai,Jakubec, Pavol,Kiesel, Michael,Janik, Matthias
, p. 1819 - 1821 (2007/10/03)
Reaction of phenylsulfonyl formamides, readily available in a single step from an aromatic aldehyde and sodium phenylsulfinate, with ketene diethyl acetal under basic conditions gives N-formyl β-amino acid esters in good yield, which can be kinetically resolved with a lipase.