869070-94-0Relevant articles and documents
New cleavable isocyanides for the combinatorial synthesis of α-amino acid analogue tetrazoles
Mayer, Josef,Umkehrer, Michael,Kalinski, Cédric,Ross, Günther,Kolb, Jürgen,Burdack, Christoph,Hiller, Wolfgang
, p. 7393 - 7396 (2005)
3-Substituted 3-isocyano propionates as new cleavable isocyanides in combinatorial tetrazole synthesis via Ugi-reaction are introduced. The obtained 5-substituted tetrazoles are transformed into carboxylic acid isosteric 5-substituted 1H-tetrazoles under basic cleavage conditions.