850074-74-7Relevant academic research and scientific papers
Benzo[b]thiophene-based histone deacetylase inhibitors
Witter, David J.,Belvedere, Sandro,Chen, Liqiang,Secrist, J. Paul,Mosley, Ralph T.,Miller, Thomas A.
, p. 4562 - 4567 (2008/02/11)
Benzo[b]thienyl hydroxamic acids, a novel class of histone deacetylase (HDAC) inhibitors, were identified via a targeted screen of small molecule hydroxamic acids. Various substitutions were explored in the C5- and C6-positions of the benzo[b]thiophene co
THIOPHENE AND BENZOTHIOPHENE HYDROXAMIC ACID DERIVATIVES
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Page/Page column 111, (2008/06/13)
The present invention relates to a novel class of hydroxamic acid derivatives having a benzothiophene or thiophene backbone. The hydroxamic acid compounds can be used to treat cancer. The hydroxamic acid compounds can also inhibit historic deacetylase and
