85012-71-1

Basic information

• Product Name: 1H-Imidazole-5-methanol, 1-methyl-4-nitro- (9CI)
• Synonyms: 1H-Imidazole-5-methanol, 1-methyl-4-nitro- (9CI)
• CAS NO: 85012-71-1
• Molecular Formula: C₅H₇N₃O₃
• Molecular Weight: 157.12738
• Product Categories: ALDEHYDE
• Mol File: 85012-71-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 239-240 °C(Solv: chloroform (67-66-3); ethanol (64-17-5))
• Boiling Point: 418.7±30.0 °C(Predicted)
• Appearance: /
• Density: 1.54±0.1 g/cm3(Predicted)
• PKA: 13.31±0.10(Predicted)
• CAS DataBase Reference: 1H-Imidazole-5-methanol, 1-methyl-4-nitro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole-5-methanol, 1-methyl-4-nitro- (9CI)(85012-71-1)
• EPA Substance Registry System: 1H-Imidazole-5-methanol, 1-methyl-4-nitro- (9CI)(85012-71-1)

Safety Data

• Hazardous Substances Data: 85012-71-1(Hazardous Substances Data)

Usage

Structure

1H-Imidazole core with a methanol group (-OH) attached to the 5-position and a methyl group (-CH3) and a nitro group (-NO2) attached to the 1-position

Derivative of imidazole

Yes

Contains a nitro group

Yes

Classification

Nitroimidazole compound

Known for antimicrobial properties

Yes

Potential applications

Pharmaceutical industry (antimicrobial and antiparasitic drugs), research and development in medicine and biotechnology.

Upstream product

• 143122-18-3 5-hydroxymethyl-2-mercapto-1-methyl-1H-imidazole 
• 87471-08-7 (E)-1-methyl-4-nitro-5-(2-phenylethenyl)-1H-imidazole 
• 38993-84-9 (1-methyl-1H-imidazol-5-yl)methanol 
• 74-88-4 methyl iodide 

Relevant articles and documents

Synthesis and Evaluation of Nitroheterocyclic Carbamate Prodrugs for Use with Nitroreductase-Mediated Gene-Directed Enzyme Prodrug Therapy

A variety of nitroheterocyclic carbamate prodrugs of phenylenediamine mustard and 5-amino-1-(chloromethyl)-3-[(5,6,7-trimethoxyindol-2-yl)carbonyl]-1, 2-dihydro-3H-benz[e]indoline (aminoseco-CBI-TMI), covering a wide range of reduction potential, were pre

Synthesis and calcium channel antagonist activity of 1,4-dihydropyridine derivatives containing 4-nitroimidazolyl substituents

Alkyl, cycloalkyl and arylalkyl ester analogues of nifedipine (CAS 21829-25-4), in which the ortho-nitro phenyl group at position 4 is replaced by 1-methyl-4-nitro-5-imidazolyl substituent, were synthesized and evaluated as calcium channel antagonists usi