850142-72-2

Basic information

• Product Name: 6-Bromo-2-fluoro-3-hydroxypyridine
• Synonyms: 6-Bromo-2-fluoro-3-hydroxypyridine;6-Bromo-2-fluoro-3-pyridinol
• CAS NO: 850142-72-2
• Molecular Formula: C5H3BrFNO
• Molecular Weight: 191.99
• Mol File: 850142-72-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 355 °C at 760 mmHg
• Flash Point: 168.5 °C
• Appearance: /
• Density: 1.891 g/cm³
• Vapor Pressure: 1.57E-05mmHg at 25°C
• Refractive Index: 1.582
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 4.46±0.10(Predicted)
• CAS DataBase Reference: 6-Bromo-2-fluoro-3-hydroxypyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Bromo-2-fluoro-3-hydroxypyridine(850142-72-2)
• EPA Substance Registry System: 6-Bromo-2-fluoro-3-hydroxypyridine(850142-72-2)

Safety Data

• Hazardous Substances Data: 850142-72-2(Hazardous Substances Data)

Usage

General Description

6-Bromo-2-fluoro-3-hydroxypyridine is a chemical compound with the molecular formula C5H3BrFNO. It is a pyridine derivative with a bromine atom, a fluorine atom, and a hydroxyl group attached to the pyridine ring. 6-Bromo-2-fluoro-3-hydroxypyridine is used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is a versatile intermediate in organic synthesis due to its unique structural features, and it is valuable for the production of diverse chemical products. Additionally, it is also used as a reagent in organic reactions to introduce functional groups in organic molecules. Overall, 6-Bromo-2-fluoro-3-hydroxypyridine is a valuable and versatile chemical compound with various industrial applications.

InChI:InChI=1/C5H3BrFNO/c6-4-2-1-3(9)5(7)8-4/h1-2,9H

Upstream product

• 174669-74-0 2-fluoro-3-hydroxypyridine 

Downstream Products

• 850142-73-3 6-bromo-2-fluoro-3-methoxypyridine 
• 1438286-73-7 2-fluoro-3-methoxy-6-(1-(3,4,5-trimethoxyphenyl)vinyl)pyridine 

Relevant articles and documents

COMT INHIBITING METHODS AND COMPOSITIONS

Compounds that inhibit COMT enzyme and pharmaceutical compositions comprising the same are provided herein. Methods of treating various psychiatric and neurological disorders with the compounds and pharmaceutical compositions described herein are also provided.

SELECTIVE OCTAHYDRO-CYCLOPENTA[C] PYRROLE NEGATIVE MODULATORS OF NR2B

Compounds that selectively negatively modulate NMDA receptors containing an NR1/NR2B subunit, pharmaceutical compositions comprising the compounds, and methods of treating a disease using the compounds are disclosed. Such diseases include, without limitation, neurological dysfunction such as Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, multiple sclerosis, and seizure disorders; emotional disorders; depression; bipolar disorder; obsessive-compulsive disorder; and other anxiety disorders.

OXAZOLOBENZIMIDAZOLE DERIVATIVES

The present invention is directed to oxazolobenzimidazole derivatives which are potentiators of metabotropic glutamate receptors, particularly the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved.