Welcome to LookChem.com Sign In|Join Free

CAS

  • or
O-2482 is a class of synthetic opioids structurally related to fentanyl and its analogs. As potent opioid receptor agonists, they exert a powerful effect on the central nervous system, leading to a high risk of overdose and death. Due to their association with illicit drug use and potential for abuse and addiction, O-2482 and its analogs have become a subject of concern for public health officials. Consequently, these chemicals have been classified as controlled substances and are regulated by legal authorities to reduce their availability and prevent misuse.

850352-53-3 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 850352-53-3 Structure
  • Basic information

    1. Product Name: O-2482
    2. Synonyms: O-2482;1-(2-naphthalenyl)-2-(1-pyrrolidinyl)-1-Pentanone;0-2482;naphthylpyrovalerone;naphyrone;nrg-1;NRG-2;1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one
    3. CAS NO:850352-53-3
    4. Molecular Formula: C19H23NO
    5. Molecular Weight: 281.39202
    6. EINECS: -0
    7. Product Categories: Research Chemical;Chemical for Research
    8. Mol File: 850352-53-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 430.5°C at 760 mmHg
    3. Flash Point: 161.4°C
    4. Appearance: /
    5. Density: 1.088g/cm3
    6. Vapor Pressure: 1.29E-07mmHg at 25°C
    7. Refractive Index: 1.596
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: O-2482(CAS DataBase Reference)
    11. NIST Chemistry Reference: O-2482(850352-53-3)
    12. EPA Substance Registry System: O-2482(850352-53-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 850352-53-3(Hazardous Substances Data)

850352-53-3 Usage

Uses

Used in Pharmaceutical Research:
O-2482 is used as a research compound for understanding the mechanisms of opioid receptors and developing new therapeutic agents with reduced risks of addiction and overdose. Its potent agonist activity provides valuable insights into the development of safer opioid medications.
Used in Forensic Toxicology:
O-2482 is utilized as a target analyte in forensic toxicology for the detection and analysis of synthetic opioid abuse and overdose cases. Its identification in biological samples helps in determining the cause of death and understanding the extent of synthetic opioid misuse in the population.
Used in Public Health Policy and Regulation:
O-2482 serves as a reference substance in the development of public health policies and regulatory measures aimed at controlling the availability and distribution of synthetic opioids. Its classification as a controlled substance helps in monitoring and preventing the misuse and abuse of these potent chemicals.
Used in Drug Rehabilitation Programs:
O-2482 is employed as an educational tool in drug rehabilitation programs to raise awareness about the dangers of synthetic opioid use and the risks associated with addiction and overdose. Its potent effects on the central nervous system highlight the importance of proper treatment and support for individuals struggling with opioid dependence.

Check Digit Verification of cas no

The CAS Registry Mumber 850352-53-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,0,3,5 and 2 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 850352-53:
(8*8)+(7*5)+(6*0)+(5*3)+(4*5)+(3*2)+(2*5)+(1*3)=153
153 % 10 = 3
So 850352-53-3 is a valid CAS Registry Number.
InChI:InChI=1/C19H23NO/c1-2-7-18(20-12-5-6-13-20)19(21)17-11-10-15-8-3-4-9-16(15)14-17/h3-4,8-11,14,18H,2,5-7,12-13H2,1H3

850352-53-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-Naphthyl)-2-(1-pyrrolidinyl)-1-pentanone

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:850352-53-3 SDS

850352-53-3Downstream Products

850352-53-3Relevant articles and documents

1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (pyrovalerone) analogues: A promising class of monoamine uptake inhibitors

Meltzer, Peter C.,Butler, David,Deschamps, Jeffrey R.,Madras, Bertha K.

, p. 1420 - 1432 (2006)

Dopamine, serotonin, and norepinephrine are essential for neurotransmission in the mammalian system. These three neurotransmitters have been the focus of considerable research because the modulation of their production and their interaction at monoamine receptors has profound effects upon a multitude of pharmacological outcomes. Our interest has focused on neurotransmitter reuptake mechanisms in a search for medications for cocaine abuse. Herein we describe the synthesis and biological evaluation of an array of 2-aminopentanophenones. This array has yielded selective inhibitors of the dopamine and norepinephrine transporters with little effect upon serotonin trafficking. A subset of compounds had no significant affinity at 5HT1A, 5HT1B, 5HT1C, D1, D2, or D3 receptors. The lead compound, racemic 1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one 4a, was resolved into its enantiomers and the S isomer was found to be the most biologically active enantiomer. Among the most potent of these DAT/NET selective compounds are the 1-(3,4-dichlorophenyl)- (4u) and the 1-naphthyl- (4t) 2-pyrrolidin-1-yl-pentan-1-one analogues.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 850352-53-3