850405-41-3

Upstream product

• 6773-29-1 dimethyl diazomalonate 
• 766-97-2 4-n-methylphenylacetylene 
• 108-59-8 malonic acid dimethyl ester 

Downstream Products

• 1020210-70-1 dimethyl 2-(4-methylphenyl)-3-trimethylsilylcycloprop-2-ene-1,1-dicarboxylate 
• 1083094-19-2 dimethyl (E)-2-[2-(4-methylphenyl)but-1-enyl]malonate 
• 1083094-22-7 dimethyl (E)-2-[2-(4-methylphenyl)pent-1-enyl]malonate 
• 1103424-35-6 (Z)-dimethyl 2-(2-chloro-1-p-tolylvinyl)malonate 
• 1103424-20-9 (Z)-dimethyl 2-(2-bromo-1-p-tolylvinyl)malonate 
• 1103424-30-1 (Z)-dimethyl 2-(2-iodo-1-p-tolylvinyl)malonate 
• 1170942-43-4 dimethyl 2-(1-(2,2-bis(phenylsulfonyl)cyclopropyl)(p-tolyl)methylidene)malonate 
• 1258299-10-3 C₁₄H₁₄O₄ 
• 161008-07-7 dimethyl 2-(2-oxo-2-(4-methylphenyl)ethylidene)propanedioate 
• 1456716-61-2 C₂₈H₂₆O₈ 
• 1453866-35-7 C₁₇H₁₈O₆ 
• 161008-04-4 methyl 2-methoxy-5-(4-tolyl)furan-3-carboxylate 

Relevant academic research and scientific papers

Regioselective oxidative ring-opening of cyclopropenyl carboxylates by visible light photoredox catalysis

Catalyzed by Ir(dFCF3ppy)2(dtbbpy)PF6, several aroyl methylidenemalonates were synthesized in good to excellent yields via visible light photoredox-catalyzed the oxidative ring-opening of cyclopropenyl carboxylate derivatives. The possible mechanism of oxidative quenching cycle was proposed.

From cyclopropenes to tetrasubstituted furans: Tandem isomerization/ alkenylation sequence with Cu/Pd relay catalysis

Pon de relay: A convenient and efficient synthesis of alkene-functionalized furans from cyclopropenes, which proceeds through an isomerization/olefination cascade sequence under copper-palladium relay catalysis, has been developed (see scheme). Copyright

Direct palladium-catalyzed arylation of cyclopropenes

The first examples of direct palladium-catalyzed arylation and heteroarylation of cyclopropenes have been demonstrated. This method allows for efficient synthesis of various tetrasubstituted cyclopropenes, incuding nonracemic cyclopropenes, which are not available via known asymmetric cyclopropenation methods. Mechanistic studies strongly suggest an electrophilic path for this Heck-type transformation. Copyright