161008-07-7

Upstream product

• 161008-04-4 methyl 2-methoxy-5-(4-tolyl)furan-3-carboxylate 
• 850405-41-3 dimethyl 2-(4-methylphenyl)cycloprop-2-ene-1,1-dicarboxylate 
• 108-59-8 malonic acid dimethyl ester 
• 6773-29-1 dimethyl diazomalonate 
• 766-97-2 4-n-methylphenylacetylene 
• 132145-64-3 dimethyl 2-(p-methylphenyl)cyclopropane-1,1-dicarboxylate 
• 1129-37-9 4-nitrobenzaldehyde oxime 
• 103-71-9 phenyl isocyanate 

Downstream Products

• 104504-72-5 methyl 2-carbomethoxy-3--propenoate 
• 104504-63-4 4,4-dimethoxycarbonyl-5-(4'-methylbenzoyl)-1-(4'-methylbenzyl)-1,2,3-triazoline 
• 104504-61-2 1-benzyl-4,4-dimethoxycarbonyl-5-(4'-methylbenzoyl)-1,2,3-triazoline 

Relevant academic research and scientific papers

Regioselective oxidative ring-opening of cyclopropenyl carboxylates by visible light photoredox catalysis

Catalyzed by Ir(dFCF3ppy)2(dtbbpy)PF6, several aroyl methylidenemalonates were synthesized in good to excellent yields via visible light photoredox-catalyzed the oxidative ring-opening of cyclopropenyl carboxylate derivatives. The possible mechanism of oxidative quenching cycle was proposed.

Method for synthesizing benzoyl methylene malonic ester compound

The invention discloses a method for synthesizing a benzoyl methylene malonic ester compound of a formula II as shown in the description. The method comprises the following steps: by taking a diester cyclopropane compound of a formula I as shown in the description as a raw material, under the action of an iron catalyst, by taking Selectfluor as an oxidant, in the presence of an acetonitrile solvent, performing stirring reaction for 8-16 hours at 70-90 DEG C, and after the reaction is completed, performing aftertreatment on a reaction liquid to obtain the benzoyl methylene malonic ester compound of the formula II as shown in the description. The method disclosed by the invention has the advantages that the raw materials are low in price and easily accessible, the process is simple, the operation is simple and convenient, environmental friendliness is achieved, the yield is high, and the functional group universality is good.

Synthesis method of benzoyl methylene malonate derivatives

The invention discloses a synthesis method of benzoyl methylene malonate derivatives as shown in a formula II. Diester-based cyclopropane compound shown in the formula I is used as a raw material, under the action of a silver catalyst, Selectfluor is taken as an oxidizing agent, and in an acetonitrile solvent, the reaction materials are stirred at 70-110 DEG C and allowed to react for 8-24 hours, and after the reaction, the reaction solution is subjected to post-treatment to prepare the benzoyl methylene malonate derivatives shown in the formula II. The synthesis method disclosed by the invention has the advantages of cheap and easily available raw materials, simple process, simplicity and convenience in operation, and being environment-friendly, high in yield, good in functional group universality and the like.

Photooxygenation of furans in water and ionic liquid solutions

Photooxygenation of differently functionalized furans is investigated in aqueous solutions and in ionic liquids [emim]Br and [bmim]BF4. The reaction is generally selective and the final products derive from rearrangement of the intermediate endoperoxides, depending mainly on the polarity and/or nucleophilic nature of the solvent.

Trapping reactions of 1-methoxyfuran endo-peroxides with 4-nitrobenzaldehyde oxime. Regio- and stereoselective synthesis of the first oxime O- ethers

The synthesis of the title compounds by dye-sensitized photooxygenation of 2-methoxyfurans in the presence of 4-nitrobenzaldehyde oxime is described. The crystal structure determination of a derivative is also reported.

Photosensitized oxidation of furans; Part 18: A simple method for a one-pot synthesis of functionalized methyl cis-4-oxoalk-2-enoates

Functionalized methyl cis-4-oxoalk-2-enoates 2 are synthesized in a one-pot procedure by singlet oxygen oxygenation of the corresponding 2-methoxyfurans 1 in methanol and reduction of the resulting hydroperoxides 4 and 5 by the sulfides 6 which are selectively oxidized into the sulfoxides 7. The synthetic method has a wide range of applicability and affords compounds 2 stereoselectively and in good yields; concomitantly the sulfoxides 7 are obtained in excellent yields.

Carbonyl Oxide Chemistry. Part 3. Regioselectivity of the First Cycloaddition of Carbonyl Oxides to Phenyl Isocyanate: One-pot Synthesis of 1,2,4-Dioxazolidin-3-ones

Carbonyl oxides 3 react with phenyl isocyanate to give the 1,2,4-dioxazolidin-3-ones 4, providing a potentially useful synthesis of a heterocyclic system which is structurally related to several biologically active products.The crystal structure of the di