85106-58-7

Basic information

• Product Name: 3H-1,2,4-Triazole-3-thione, 4-amino-5-(4-bromophenyl)-2,4-dihydro-
• Synonyms: 4-amino-5-(4-bromophenyl)-4H-1,2,4-triazole-3-thiol;5-p-bromophenyl-4-amino-3-mercapto-1,2,4-triazole;4-Amino-5-(4-bromo-phenyl)-4H-[1,2,4]triazole-3-thiol
• CAS NO: 85106-58-7
• Molecular Formula: C8H7BrN4S
• Molecular Weight: 271.14
• Mol File: 85106-58-7.mol
• Article Data: 20

Chemical Properties

• Melting Point: 204 - 205 °C (ethanol)
• CAS DataBase Reference: 3H-1,2,4-Triazole-3-thione, 4-amino-5-(4-bromophenyl)-2,4-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 3H-1,2,4-Triazole-3-thione, 4-amino-5-(4-bromophenyl)-2,4-dihydro-(85106-58-7)
• EPA Substance Registry System: 3H-1,2,4-Triazole-3-thione, 4-amino-5-(4-bromophenyl)-2,4-dihydro-(85106-58-7)

Safety Data

• Hazardous Substances Data: 85106-58-7(Hazardous Substances Data)

Upstream product

• 75-15-0 carbon disulfide 
• 85106-56-5 p-bromobenzoylhydrazinyl dithiocarbamate potassium salt 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 5933-32-4 4-bromobenzoic acid hydrazide 
• 82892-00-0 N-(4-bromobenzoyl)imidazole 
• 586-76-5 4-Bromobenzoic acid 
• 5798-75-4 Ethyl 4-bromobenzoate 
• 41421-19-6 5-(4-bromo-phenyl)-[1,3,4]-oxadiazole-2-thiol 
• 2231-57-4 Thiocarbohydrazide 

Downstream Products

• 1293362-47-6 methyl 3-(3-(4-bromophenyl)-5-thioxo-1H-1,2,4-triazol-4-ylimino)cholanate 
• 1400796-66-8 methyl 3α-(2-(4-amino-3-(4-bromophenyl)-5-thioxo-4,5-dihydro-1,2,4-triazol-1-yl)acetoxy)-12α-hydroxycholanate 
• 1427500-99-9 3-(4-bromophenyl)-6-(furan-3-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 
• 947858-66-4 3-(4-bromophenyl)-6-(pyridin-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 
• 950256-52-7 3-(4-bromophenyl)-6-(pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 
• 1427468-62-9 3-(4-bromophenyl)-6-(3,5-difluoropyridin-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 
• 1427468-64-1 3-(4-bromophenyl)-6-(thiophen-2-ylmethyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 

Relevant articles and documents

Schiff Base Functionalized 1,2,4-Triazole and Pyrene Derivative for Selective and Sensitive Detection of Cu2+?ion?in the Mixed Organic- Aqueous Media

We have prepared Schiff base functionalized 1,2,4-triazole and pyrene derivative for selective, sensitive, and naked eye colorimetric detection of Cu2+ in the mixed organic- aqueous media. Amongst the 18 different metal ions studied for absorption and fluorescence titration, only Cu2+ ion encourages the modification in spectral properties of Schiff base functionalized 1,2,4-Triazole and Pyrene Probe. The stoichiometric ratio of the TP-Cu2+ complex was determined to be 2:1 according to Job’s plot. The lower detection limit estimated for Cu2+ is 0.234?nM which shows excellent sensitivity and selectivity of the present analytical method towards detection of Cu2+ ion in the mixed organic-aqueous media. The present approach has been successfully utilized for the quantitative determination of Cu2+ ion from environmental aqueous solution.

INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE

Compounds and salts thereof which are acyl-sulfonamides or certain carboxylic acids and which inhibit microbial growth or attenuate the virulence of pathogenic microorganisms and which inhibit UDP-galactopyranose mutase (UGM). Compounds of the invention include 2-aminothiazoles and triazolothiadiazines, particularly 3,6,7-substituted-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines, and 2-amino and salts thereof. Methods for inhibiting growth or attenuating virulence of microbial pathogens including mycobacterium, for example, M. tuberculosis and M. smegmatis and Klebsiella, for example, Klebsiella pneumoniae. Methods for inhibiting eukaryotic human and animal pathogens, and fungi and nematodes in particular. Methods for treatment of infections by prokaryotic and eukaryotic pathogens employing compounds of the invention.

Synthesis of Triazole Based Novel Ionic Liquids and Salts

-