851178-96-6 Usage
Uses
Used in Organic Synthesis:
4-Bromo-2,3,5-trifluoropyridine is used as a building block in organic synthesis for its strong electron-withdrawing properties, which facilitate the formation of C-C and C-N bonds.
Used in Pharmaceutical Research:
4-Bromo-2,3,5-trifluoropyridine is used as a key intermediate in the synthesis of various bioactive molecules in pharmaceutical research.
Used in Agrochemical Research:
4-Bromo-2,3,5-trifluoropyridine is used as a key intermediate in the synthesis of bioactive molecules in agrochemical research.
Used in Materials Science:
4-Bromo-2,3,5-trifluoropyridine is used in the development of organic light-emitting diodes (OLEDs) and other electronic devices in materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 851178-96-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,1,1,7 and 8 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 851178-96:
(8*8)+(7*5)+(6*1)+(5*1)+(4*7)+(3*8)+(2*9)+(1*6)=186
186 % 10 = 6
So 851178-96-6 is a valid CAS Registry Number.
InChI:InChI=1/C5HBrF3N/c6-3-2(7)1-10-5(9)4(3)8/h1H
851178-96-6Relevant articles and documents
Removal of fluorine from and introduction of fluorine into polyhalopyridines: An exercise in nucleophilic hetarenic substitution
Bobbio, Carla,Rausis, Thierry,Schlosser, Manfred
, p. 1903 - 1910 (2005)
Starting from six industrially available fluorinated pyridines, an expedient access to all three tetrafluoropyridines (2-4), all six trifluoropyridines (5-10), and the five non-commercial difluoropyridines (11-14 and 16) was developed. The methods employed for the selective removal of fluorine from polyfluoropyridines were the reduction by metals or complex hydrides and the site-selective replacement by hydrazine followed by dehydrogenation-dediazotation or dehydrochlorination-dediazotation. To introduce an extra fluorine atom, a suitable precursor was metalated and chlorinated before being subjected to a chlorine/ fluorine displacement process.
