4-Bromo-2,3,5-trifluoropyridine

Base Information

Chemical Name:4-Bromo-2,3,5-trifluoropyridine
CAS No.:851178-96-6
Molecular Formula:C₅HBrF₃N
Molecular Weight:211.969
Hs Code.:2933399990
Mol file:851178-96-6.mol

Synonyms:PC9693;QC-6964;

Suppliers and Price of 4-Bromo-2,3,5-trifluoropyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Bromo-2,3,5-trifluoropyridine 95+%
1g
$ 672.00

Chemenu
4-bromo-2,3,5-trifluoropyridine 95%
1g
$ 635.00

American Custom Chemicals Corporation
4-BROMO-2,3,5-TRIFLUOROPYRIDINE 95.00%
250MG
$ 1482.11

Alichem
4-Bromo-2,3,5-trifluoropyridine
1g
$ 2923.95

Alichem
4-Bromo-2,3,5-trifluoropyridine
250mg
$ 950.60

Total 12 raw suppliers

Chemical Property of 4-Bromo-2,3,5-trifluoropyridine

Chemical Property:

Vapor Pressure:3.43mmHg at 25°C
Boiling Point:158.2oC at 760 mmHg
PKA:-1.44±0.10(Predicted)
Flash Point:49.5oC
PSA：12.89000
Density:1.901g/cm3
LogP:2.26140
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

4-Bromo-2,3,5-trifluoropyridine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-Bromo-2,3,5-trifluoropyridine

There total 4 articles about 4-Bromo-2,3,5-trifluoropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 76469-41-5
2,3,5‐trifluoropyridine

: 851178-96-6
4-bromo-2,3,5-trifluoropyridine

Guidance literature:: 2,3,5‐trifluoropyridine; With n-butyllithium; In tetrahydrofuran; hexane; at -75 ℃; for 2h;

With bromine; at -75 ℃; for 1h;
DOI:10.1002/chem.200400837

Reference yield:

: 851179-05-0
3,5,6-trifluoro-2-hydrazinopyridine

: 851178-96-6
4-bromo-2,3,5-trifluoropyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: 65 percent / aq. CuSO₄ / Heating

2.1: BuLi / tetrahydrofuran; hexane / 2 h / -75 °C

2.2: 78 percent / Br₂ / 1 h / -75 °C

With n-butyllithium; copper(II) sulfate; In tetrahydrofuran; hexane;
DOI:10.1002/chem.200400837

Reference yield:

: 2875-18-5
2,3,5,6-tetrafluoropyridine

: 851178-96-6
4-bromo-2,3,5-trifluoropyridine

Guidance literature:: Multi-step reaction with 3 steps

1.1: 88 percent / hydrazine monohydrate / ethanol / 2 h / Heating

2.1: 65 percent / aq. CuSO₄ / Heating

3.1: BuLi / tetrahydrofuran; hexane / 2 h / -75 °C

3.2: 78 percent / Br₂ / 1 h / -75 °C

With n-butyllithium; hydrazine hydrate; copper(II) sulfate; In tetrahydrofuran; ethanol; hexane;
DOI:10.1002/chem.200400837