851189-86-1

Upstream product

• 141-79-7 4-methyl-pent-3-en-2-one 
• 130043-07-1 2-<(tert-butyldimethylsilyl)oxy>-4,4-dimethyl-1,3-butadiene 
• 67170-56-3 3-methyl-1-oxocyclohex-2-en-4-acetic acid methyl ester 

Downstream Products

• 16556-46-0 3,3,5,5-Tetramethyl-4-acetyl-1-cyclohexanon 

Relevant academic research and scientific papers

Stepwise acid-promoted double-Michael process: An alternative to Diels-Alder cycloadditions for hindered silyloxydiene-dienophile pairs

(Chemical Equation Presented) The hindered diene 1 reacts with 3-methylcyclohexenone 6 catalyzed by triflimide to produce the Mukaiyama Michael product 7 (low-temperature quenching) or the [4+2] cycloadduct 8 (quenching at 0°C). Reaction of the hindered d

Synthesis of highly substituted cyclohexenes via mixed Lewis acid-catalyzed Diels-Alder reactions of highly substituted dienes and dienophiles

(Chemical Equation Presented) A high-yielding method is described for the rapid synthesis of very hindered cyclohexenes by the Diels-Alder reaction of hindered silyloxy dienes and dienophiles using the mixed Lewis acid catalyst system (AlBr3/AlMe3). Thus, reaction of the hindered diene 4 with various substituted enones gave good yields of the expected cycloadducts even though both partners are quite sterically hindered.