85122-21-0 Usage
General Description
2-Methoxystypandrone is a naturally occurring chemical compound derived from Stypandra imbricata, a member of the lily family. It is classified as a styrylpyrone, a type of organic compound with a distinctive aromatic ring structure and side chain. 2-Methoxystypandrone has demonstrated various biological activities, including anti-inflammatory, anti-fungal, and anti-viral properties. Additionally, it has shown potential as an anti-cancer agent, with studies suggesting its ability to inhibit the growth of cancer cells. Its diverse pharmacological activities make it a valuable target for further research and potential development of new pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 85122-21-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,1,2 and 2 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 85122-21:
(7*8)+(6*5)+(5*1)+(4*2)+(3*2)+(2*2)+(1*1)=110
110 % 10 = 0
So 85122-21-0 is a valid CAS Registry Number.
InChI:InChI=1/C14H12O5/c1-6-4-8-12(14(18)11(6)7(2)15)9(16)5-10(19-3)13(8)17/h4-5,18H,1-3H3
85122-21-0Relevant articles and documents
Discovery, total synthesis, HRV 3C-protease inhibitory activity, and structure-activity relationships of 2-Methoxystypandrone and its analogues
Singh, Sheo B,Graham, Pia L,Reamer, Robert A,Cordingley, Michael G
, p. 3143 - 3146 (2001)
2-Methoxystypandrone, a naphthoquinone, was isolated from a Chinese herb Polygonum cuspidatum by bioassay guided fractionation using HRV 3C-protease assay. It showed an IC50 value of 4.6 μM and is moderately selective. A new 10-step, total synthesis of 2-methoxystypandrone was accomplished in 45% overall yield using a Diels-Alder approach. Several analogues of this compound were prepared. Isolation, synthesis and HRV 3C-protease structure-activity relationships of these compounds have been described.
