85127-60-2Relevant academic research and scientific papers
3-Aminooxetanes: Versatile 1,3-amphoteric molecules for intermolecular annulation reactions
Feng, Qiang,Lai, Zengwei,Sun, Jianwei,Zhang, Renwei
, p. 9945 - 9949 (2020/10/06)
Despite the versatility of amphoteric molecules, stable and easily accessible ones are still limitedly known. As a result, the discovery of new amphoteric reactivity remains highly desirable. Herein we introduce 3-aminooxetanes as a new family of stable and readily available 1,3-amphoteric molecules and systematically demonstrated their amphoteric reactivity toward polarized π-systems in a diverse range of intermolecular [3 + 2] annulations. These reactions not only enrich the reactivity of oxetanes, but also provide convergent access to valuable heterocycles.
Regioselective Aziridine Ring Expansions
Clough, Stuart C.,Solomon, Robert,Crews, Elain,Jaques, Larry,Johnson, Ashby,Forehand, John
, p. 1489 - 1491 (2007/10/02)
1-Phenylmethyl-2-hydroxymethylaziridine (1) undergoes regioselective reactions with carbon disulfide to form thiazolidinethiones.Deuterium labeling experiments suggest that the reaction proceeds exclusively via aziridinium ring expansion.The regiospecificity appears to be electronically controlled.
