851314-93-7

Upstream product

• 217196-31-1 4-(5-fluoro-2-methoxyphenyl)-4-methyl-2-oxopentanoic acid 
• 98919-68-7 (1R,2S)-trans-2-phenylcyclohexanol 
• 459-60-9 1-fluoro-4-methoxybenzene 
• 566920-34-1 4-(5-fluoro-2-methoxyphenyl)-4-methyl-2-oxopentanoic acid ethyl ester 
• 851314-92-6 2-(2-chloro-1,1-dimethylethyl)-4-fluoro-1-methoxybenzene 

Downstream Products

• 851314-94-8 (αR)-5-fluoro-2-methoxy-γ,γ-dimethyl-α-(trifluoromethyl)-α-[(trimethylsilyl)oxy]-benzenebutanoic acid (1R,2S)-2-phenylcyclohexyl ester 
• 851314-97-1 (2R)-2-[2-(5-fluoro-2-methoxyphenyl)-2-methylpropyl]-2-(trifluoromethyl)-oxirane 
• 851314-96-0 (R)-4-(5-fluoro-2-methoxyphenyl)-4-methyl-2-trifluoromethylpentane-1,2-diol 
• 851314-95-9 (S)-4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-trifluoromethylpentanoic acid 

Relevant academic research and scientific papers

Practical stereoselective synthesis of an α-trifluoromethyl-α- alkyl epoxide via a diastereoselective trifluoromethylation reaction

A practical stereoselective synthesis is reported for an α-trifluoromethyl-α-alkyl epoxide (1), which is an important pharmaceutical intermediate. The key step involves a chiral auxiliary-controlled asymmetric trifluoromethylation reaction for the introdu

STEREOSELECTIVE SYNTHESIS OF CERTAIN TRIFLUOROMETHYL-SUBSTITUTED ALCOHOLS

A process for stereoselective synthesis of compounds of Formula (X) wherein: R1 is an aryl or heteroaryl group, each optionally independently substituted with one to three substituent groups, wherein each substituent group of R1 is i