851528-79-5 Usage
Uses
Used in Pharmaceutical Industry:
Seladelpar is used as a lipid-altering agent for the treatment of dyslipidemia and other lipid metabolism disorders. It modulates lipid levels by activating PPAR-δ receptors, which play a crucial role in lipid homeostasis and energy metabolism. This action helps improve the overall lipid profile and reduce the risk of cardiovascular diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 851528-79-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,1,5,2 and 8 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 851528-79:
(8*8)+(7*5)+(6*1)+(5*5)+(4*2)+(3*8)+(2*7)+(1*9)=185
185 % 10 = 5
So 851528-79-5 is a valid CAS Registry Number.
851528-79-5Relevant articles and documents
Discovery of para-alkylthiophenoxyacetic acids as a novel series of potent and selective PPARδ agonists
Zhang, Rui,Wang, Aihua,DeAngelis, Alan,Pelton, Patricia,Xu, Jun,Zhu, Peifang,Zhou, Lubing,Demarest, Keith,Murray, William V.,Kuo, Gee-Hong
, p. 3855 - 3859 (2008/02/13)
A novel series of potent and selective PPARδ agonists, para-alkylthiophenoxyacetic acids, was identified. The synthesis and structure-activity relationships are described.
4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS
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Page/Page column 74-75; 76, (2010/02/11)
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
