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851531-99-2

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851531-99-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 851531-99-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,1,5,3 and 1 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 851531-99:
(8*8)+(7*5)+(6*1)+(5*5)+(4*3)+(3*1)+(2*9)+(1*9)=172
172 % 10 = 2
So 851531-99-2 is a valid CAS Registry Number.

851531-99-2Relevant articles and documents

Potential antitumor agents. 37. Synthesis and antitumor activity of guanylhydrazones from imidazo[2,1-b]thiazoles and from the new heterocyclic system thiazolo[2′,3′:2,3]imidazo[4,5-c]quinoline

Andreani, Aldo,Granaiola, Massimiliano,Leoni, Alberto,Locatelli, Alessandra,Morigi, Rita,Rambaldi, Mirella,Lenaz, Giorgio,Fato, Romana,Bergamini, Christian,Farruggia, Giovanna

, p. 3085 - 3089 (2007/10/03)

This paper reports synthesis and antitumor activity of new guanylhydrazones from imidazo[2,1-b]thiazoles and from the new heterocyclic system thiazolo[2′,3′:2,3]imidazo[4,5-c]quinoline. The compounds were tested as potential antitumor agents at the National Cancer Institute. The effect of the guanylhydrazone of 2-chloro-6-(2,5-dimethoxy-4-nitrophenyl) imidazo[2,1-6]thiazole-5-carbaldehyde (41) was investigated, and it was found to be an inhibitor of Complex III of the mitochondrial respiratory chain and is able to induce apoptosis in the cell lines HT29 and HL60.

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