851544-48-4

Upstream product

• 690229-10-8 (2R,5S)-5-but-3-enyl-pyrrolidine-1,2-dicarboxylic acid di-tert-butyl ester 
• 228579-91-7 (2S)-di-tert-butyl 5-methoxypyrrolidine-1,2-dicarboxylate 
• 851544-32-6 (2R,5S)-5-but-3-enyl-1-methoxyoxalylpyrrolidine-2-carboxylic acid tert-butyl ester 
• 851544-38-2 (2R,5S)-5-but-3-enyl-1-(2-hydroxyacetyl)pyrrolidine-2-carboxylic acid tert-butyl ester 
• 851544-63-3 (2S,5S)-5-But-3-enyl-1-(2-oxo-acetyl)-pyrrolidine-2-carboxylic acid tert-butyl ester 
• 29601-98-7 N-benzylhydroxylamine hydrochloride 

Downstream Products

• 1190769-02-8 C₃₄H₄₅N₇O₅ 
• 1099616-09-7 C₁₉H₂₄N₂O₄ 

Relevant academic research and scientific papers

PEPTIDOMIMETIC COMPOUNDS, STEREOSELECTIVE PROCESS FOR THEIR PREPARATION, THEIR USE AS BIOLOGICALLY ACTIVE SYNTHETIC INTERMEDIATES

The invention relates to novel cyclic peptidomimetic compounds having an azabicycloalkane structure, useful as intermediates in the preparation of αVΒ3 and αVΒ5 integrin antagonists, intended, for example, for the treatment of altered angiogenic phenomena

Functionalized azabicycloalkane amino acids by nitrone 1,3-dipolar intramolecular cycloaddition

An efficient and operationally simple method for the synthesis of functionalized azaoxobicyclo-[X.3.0]alkane amino acids has been devised. The key step is an intramolecular nitrone cycloaddition on 5-allyl- or 5-homoallylproline that was found to be compl