852064-26-7

Upstream product

• 33598-22-0 1-Phenyl-3-methylprop-2-yne 
• 768-33-2 phenyldimethylsilyl chloride 
• 184370-59-0 (E)-1-iodo-4-phenyl-1-butene 

Downstream Products

• 852064-38-1 (E)-2-methyl-7-phenylhept-4-en-2-one 
• 27066-35-9 (E)-1,4-diphenylbut-1-ene 
• 134273-12-4 (2E)-5-phenyl-2-pentanophenone 
• 182692-62-2 (E)-2,2-dimethyl-7-phenyl-4-hepten-3-one 
• 5272-18-4 dimethylphenylsilanol 
• 56-33-7 1,1,3,3-tetramethyl-1,3-diphenyldisiloxane 
• 768-33-2 phenyldimethylsilyl chloride 
• 852064-40-5 (E)-4-phenyl-1-trimethylsilylbut-1-en-1-yl benzoate 
• 93-97-0 benzoic acid anhydride 
• 1239987-82-6 (E)‐1‐(4‐methoxyphenyl)‐5‐phenylpent‐2‐en‐1‐one 
• 917575-20-3 (E)-1-cyclopropyl-5-phenylpent-2-en-1-one 
• 33046-41-2 (E)-6-phenyl-3-hexen-2-one 
• 141191-77-7 trans-1-Phenyl-3-nonen-5-one 

Relevant academic research and scientific papers

Direct Access to α,β-Unsaturated Ketones via Rh/MgCl2-Mediated Acylation of Vinylsilanes

We report herein the facile and practical construction of α,β-unsaturated ketones via rhodium-catalyzed direct acylation of vinylsilanes with readily available and abundant carboxylic acids. This protocol features access to a diverse array of synthetically useful functionalities with moderate to excellent yields. More importantly, the late-stage functionalization of pharmaceuticals was also realized with synthetically useful yield.

Copper-Catalyzed Cross-Coupling of Vinyliodonium Salts and Zinc-Based Silicon Nucleophiles

A silylation of vinyliodonium salts using zinc-based silicon reagents as nucleophiles is reported. This cross-coupling is catalyzed by copper, and vinylsilanes are obtained in high yield likely following a Cu(I)/Cu(III) reaction mechanism. The procedure i

Rhodium-catalyzed acylation of vinylsilanes with acid anhydrides

A catalytic acylation of vinylsilane with acid anhydride is accomplished by the use of [RhCl(CO)2]2, in which the transmetalation between vinylsilane and rhodium(I) carbonyl complex plays a key role. The application of this acylation reaction to (1-acyloxyvinyl)silanes provides synthetic methods for α-acyloxy enones, α-diketones, and their derivatives.