917575-20-3

Basic information

• Product Name: 2-Penten-1-one, 1-cyclopropyl-5-phenyl-, (2E)-
• CAS NO: 917575-20-3
• Molecular Formula: C14H16O
• Molecular Weight: 200.28
• Mol File: 917575-20-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-Penten-1-one, 1-cyclopropyl-5-phenyl-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Penten-1-one, 1-cyclopropyl-5-phenyl-, (2E)-(917575-20-3)
• EPA Substance Registry System: 2-Penten-1-one, 1-cyclopropyl-5-phenyl-, (2E)-(917575-20-3)

Safety Data

• Hazardous Substances Data: 917575-20-3(Hazardous Substances Data)

Upstream product

• 104-53-0 3-phenyl-propionaldehyde 
• 67-56-1 methanol 
• 765-43-5 Cyclopropyl methyl ketone 
• 36884-28-3 5-phenyl-1-pentanal 
• 184370-59-0 (E)-1-iodo-4-phenyl-1-butene 
• 33598-22-0 1-Phenyl-3-methylprop-2-yne 
• 1759-53-1 cyclopropanecarboxylic acid 
• 852064-26-7 (E)-dimethyl(phenyl)(4-phenylbut-1-en-1-yl)silane 
• 7691-76-1 1-cyclopropyl-2-(triphenyl-λ⁵-phosphanylidene)ethan-1-one 

Relevant articles and documents

Direct Access to α,β-Unsaturated Ketones via Rh/MgCl2-Mediated Acylation of Vinylsilanes

We report herein the facile and practical construction of α,β-unsaturated ketones via rhodium-catalyzed direct acylation of vinylsilanes with readily available and abundant carboxylic acids. This protocol features access to a diverse array of synthetically useful functionalities with moderate to excellent yields. More importantly, the late-stage functionalization of pharmaceuticals was also realized with synthetically useful yield.

Enantioselective NiH/Pmrox-Catalyzed 1,2-Reduction of α,β-Unsaturated Ketones

The enantioselective 1,2-reduction of α,β-unsaturated ketones was achieved using a NiH catalyst in the presence of pinacolborane. This mild process represents a general method to access a wide variety of structurally diverse α-chiral allylic alcohols in excellent yields and enantioselectivity, as well as very high levels of ambidoselectivity for 1,2- over 1,4-reduction. Furthermore, for reactions on a 10 mmol scale, catalyst loadings as low as 0.5 mol % could be employed to deliver product without any detrimental effect on the yield, enantio-, or ambidoselectivity.

L-proline-catalyzed one-pot three-component reaction for the synthesis of β-alkoxy ketones

β-Alkoxy ketones were prepared by a one-pot three-component reaction of aliphatic aldehydes, ketones, and alcohols catalyzed by L-proline. Steric effects on the reaction were studied with substituted ketones, aldehydes, and alcohols, and the results indicate that reactions employing methyl ketones, α-unsubstituted aliphatic aldehydes and methanol produce the β-alkoxy ketones in the best yields when L-proline is used as the catalyst. The reaction mechanism is discussed. Georg Thieme Verlag Stuttgart.