852213-23-1Relevant articles and documents
Synthesis of a simplified analogue of eleutherobin via a Claisen rearrangement and ring closing metathesis strategy
Chiang, Gary C. H.,Bond, Andrew D.,Ayscough, Andrew,Pain, Gilles,Ducki, Sylvie,Holmes, Andrew B.
, p. 1860 - 1862 (2005)
The enantioselective synthesis of a simplified eleutherobin analogue 7 by ring closing metathesis (RCM) of the 2,9-divinyl-substituted tetrahydro-oxonin 5 is described; the analogue 7 and an advanced intermediate 15 revealed microtubule stabilising proper