852233-79-5

Upstream product

• 87081-52-5 ethyl 4-amino-3-hydroxybenzoate 
• 717-01-1 ethyl 3-hydroxy-4-nitro-benzoate 
• 619-14-7 3-hydroxy-4-nitro-benzoic acid 
• 852233-80-8 ethyl 4-[(2,2-dichloroacetyl)amino]-3-hydroxybanzoate 

Downstream Products

• 852233-81-9 ethyl (3S)-3-[({2-[(4-cyanobenzyl)oxo]-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-7-yl}carbonyl)amino]-3-phenylpropanoate 
• 852233-83-1 ethyl 2-[(4-cyanobenzyl)oxy]-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-7-carboxylate 
• 852233-84-2 2-[(4-cyanobenzyl)oxy]-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-7-carboxylic acid 

Relevant academic research and scientific papers

Toward a novel class of antithrombotic compounds with dual function. Discovery of 1,4-benzoxazin-3(4H)-one derivatives possessing thrombin inhibitory and fibrinogen receptor antagonistic activities

A novel class of potential antithrombotic compounds with moderate thrombin inhibitory and fibrinogen receptor antagonistic activity is described. Combination of anticoagulant and antiaggregatory activity in the same molecular entity is presented as a new

ANTITHROMBOTIC COMPOUNDS WITH DUAL FUNCTION

The present invention comprises compounds of the general formula (I) : and pharmaceutically acceptable salts thereof, wherein the substituents have in the description specified meaning. The compounds are used as antithrombotic agents possessing inhibitory