852619-15-9Relevant academic research and scientific papers
CO extrusion in homogeneous gold catalysis: Reactivity of gold acyl species generated through water addition to gold vinylidenes
Bucher, Janina,St?sser, Tim,Rudolph, Matthias,Rominger, Frank,Hashmi, A. Stephen K.
, p. 1666 - 1670 (2015/01/30)
Herein, we describe a new gold-catalyzed decarbonylative indene synthesis. Synergistic σ,π-activation of diyne substrates leads to gold vinylidene intermediates, which upon addition of water are transformed into gold acyl species, a type of organogold compound hitherto only scarcely reported. The latter are shown to undergo extrusion of CO, an elementary step completely unknown for homogeneous gold catalysis. By tuning the electronic and steric properties of the starting diyne systems, this new reactivity could be exploited for the synthesis of indene derivatives in high yields.
Gold-catalyzed intramolecular alkyne cycloisomerization cascade: Direct synthesis of aryl-annulated[a]carbazoles from aniline-substituted diethynylarenes
Hirano, Kimio,Inaba, Yusuke,Watanabe, Toshiaki,Oishi, Shinya,Fujii, Nobutaka,Ohno, Hiroaki
supporting information; experimental part, p. 368 - 372 (2010/06/11)
Aniline-substituted diethynylarenes, which are readily synthesized through Sonogashira coupling reactions from commercially available 1,2-dihaloarenes, directly produce aryl- and heteroaryl-annulated [a]carbazoles by the gold-catalyzed intramolecular casc
Cytotoxicities, cell cycle and caspase evaluations of 1,6-diaryl-3(Z)- hexen-1,5-diynes, 2-(6-aryl-3(Z)-hexen-1,5-diynyl)anilines and their derivatives
Lin, Chi-Fong,Lo, Yu-Hsiang,Hsieh, Ming-Chu,Chen, Yi-Hua,Wang, Jeh-Jeng,Wu, Ming-Jung
, p. 3565 - 3575 (2007/10/03)
Compounds 3, 6-7, 9-10, 15-17, and 20-21 showed growth inhibition effects on a full panel of 60 human cancer cell lines, and most of the average IC 50 values of the indicated analogues were from 0.01 to 96.6 μM, in which analogues 16 and 17 re
