852812-69-2Relevant academic research and scientific papers
Synthesis and biological evaluation of N-{4-[5-(2,4-diamino-6-oxo-1,6- dihydropyrimidin-5-yl)-2-(2,2,2-trifluoroacetyl)pentyl]benzoyl}-L-glutamic acid as a potential inhibitor of GAR Tfase and the de novo purine biosynthetic pathway
Cheng, Heng,Hwang, Inkyu,Chong, Youhoon,Tavassoli, Ali,Webb, Michael E.,Zhang, Yan,Wilson, Ian A.,Benkovic, Stephen J.,Boger, Dale L.
, p. 3593 - 3599 (2007/10/03)
The synthesis and evaluation of N-{4-[5-(2,4-diamino-6-oxo-1,6- dihydropyrimidin-5-yl)-2-(2,2,2-trifluoroacetyl)pentyl]benzoyl}-l-glutamic acid (2) as an inhibitor of glycinamide ribonucleotide transformylase (GAR Tfase) and aminoimidazole carboxamide rib
