852818-41-8

Basic information

• Product Name: C₁₂H₈FN₃O
• Synonyms: C₁₂H₈FN₃O
• CAS NO: 852818-41-8
• Molecular Weight: 229.213
• Mol File: 852818-41-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₂H₈FN₃O(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₈FN₃O(852818-41-8)
• EPA Substance Registry System: C₁₂H₈FN₃O(852818-41-8)

Safety Data

• Hazardous Substances Data: 852818-41-8(Hazardous Substances Data)

Upstream product

• 221148-38-5 methyl 3-(3-fluorophenyl)prop-2-ynoate 
• 221148-39-6 2-(3-fluoro-phenyl)-6-methoxy-pyrazolo[1,5-b]pyridazine-3-carboxylic acid methyl ester 
• 221148-40-9 2-(3-fluoro-phenyl)-6-methoxy-pyrazolo[1,5-b]pyridazine-3-carboxylic acid 
• 221148-37-4 1-(2,2-Dibromo-vinyl)-3-fluoro-benzene 
• 221148-41-0 3-bromo-2-(3-fluoro-phenyl)-6-methoxy-pyrazolo[1,5-b]pyridazine 

Downstream Products

• 221148-42-1 6-difluoromethoxy-2-(3-fluoro-phenyl)-pyrazolo[1,5-b]pyridazine 
• 221148-50-1 6-difluoromethoxy-2-(3-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine 

Relevant articles and documents

USE OF CYCLOOXYGENASE-2 INHIBITORS FOR THE TREATMENT OF DEPRESSIVE DISORDERS

The invention concerns the use of compounds of formula (I), (II) and (III): which are COX-2 (cyclooxygenase-2) inhibitors, and pharmaceutically acceptable salts or solvates thereof, for the treatment of depressive disorders in combination with an effective amount of a second component which is a selective serotonin reuptake inhibitor.