852878-89-8Relevant academic research and scientific papers
Copper-catalyzed C(sp3)-C(sp3) bond formation using a hypervalent iodine reagent: An efficient allylic trifluoromethylation
Wang, Xi,Ye, Yuxuan,Zhang, Songnan,Feng, Jiajie,Xu, Yan,Zhang, Yan,Wang, Jianbo
supporting information; experimental part, p. 16410 - 16413 (2011/11/29)
An efficient copper-catalyzed allylic trifluoromethylation reaction has been developed. This reaction provides a general and straightforward way to synthesize allylic trifluoromethylated compounds under mild conditions.
MACROCYCLIC LACTAMS AND PHARMACEUTICAL USE THEREOF
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Page/Page column 62-63, (2008/06/13)
The present invention relates to novel macrocyclic compounds of the formula (I) wherein R1, R2, R3, U, V, W, X, Y, Z and n are as defined in the specification, the number of ring atoms included in the macrocyclic ring being 14, 15, 16 or 17, in free base form or in acid addition salt form, to their preparation, to their use as pharmaceuticals and to pharma-ceutical compositions comprising them.
