85291-68-5Relevant academic research and scientific papers
Synthesis of bridging hydrides of phenyl-functionalized diiron propanedithiolate complexes with 1,2-bis(diphenylphosphine)ethylene or 1,2-bis(diphenylphosphine)ethane ligands
Li, Chang-Gong,Zhang, Gao-Feng,Zhu, Yong,Xue, Feng,Shang, Jing-Yan,Cui, Mao-Jin,Lou, Tian-Jun
, p. 477 - 484 (2015)
Abstract Reaction of 2-phenyl-1,3-dibromopropane with in situ generated (μ-SLi)2Fe2(CO)6 yielded a known complex [(μ-SCH2)2CHC6H5]Fe2(CO)6 (A). Displacement of two carbonyls from complex A by cis-1,2-bis(diphenylphosphine)ethylene (dppv) or 1,2-bis(diphenylphosphine)ethane (dppe) in the presence of Me3NO·2H2O gave two chelate complexes [(μ-SCH2)2CHC6H5]Fe2(CO)4(κ 2-dppv), [A(κ 2-dppv)] and [(μ-SCH2)2CHC6H5]Fe2(CO)4(κ 2-dppe), [A(κ 2-dppe)], respectively. Protonation of the diiron centers of [A(κ 2-dppv)] and [A(κ 2-dppe)] using an excess of HBF4·Et2O in dichloromethane at room temperature gave the bridging hydrides [(μ-H)A(κ 2-dppv)]BF4 and [(μ-H)A(κ 2-dppe)]BF4. The complexes [(μ-H)A(κ 2-dppv)]BF4, [A(κ 2-dppe)] and [(μ-H)A(κ 2-dppe)]BF4 were characterized by elemental analysis and spectroscopic methods, and [(μ-H)A(κ 2-dppv)]BF4 and [(μ-H)A(κ 2-dppe)]BF4 were also characterized by X-ray crystallography. The electrochemical behavior of [(μ-H)A(κ 2-dppv)]BF4 was investigated by cyclic voltammetry, and the catalytic electrochemical reduction in protons from trifluoroacetic acid or p-methylbenzene sulfonic acid to give hydrogen was investigated.
Copper-Catalyzed Oxyalkynylation of C-S Bonds in Thiiranes and Thiethanes with Hypervalent Iodine Reagents
Borrel, Julien,Pisella, Guillaume,Waser, Jerome
supporting information, p. 422 - 427 (2020/01/31)
We report the oxyalkynylation of thiiranes and thietanes using ethynylbenziodoxolone reagents (EBXs) to readily access functionalized building blocks bearing an alkynyl, a benzoate, and an iodide group. The reaction proceeds with high atom efficiency most
Diverse ring opening of thietanes and other cyclic sulfides: An electrophilic aryne activation approach
Zheng, Tianyu,Tan, Jiajing,Fan, Rong,Su, Shuaisong,Liu, Binbin,Tan, Chen,Xu, Kun
supporting information, p. 1303 - 1306 (2018/02/14)
Organosulfides are a common class of structure units in bioactive molecules and functional materials motivating continuous developments of efficient synthetic methods. Herein, we report an electrophilic aryne-activated ring opening protocol of one or two
Haloalkane dehalogenase catalysed desymmetrisation and tandem kinetic resolution for the preparation of chiral haloalcohols
Westerbeek, Alja,Van Leeuwen, Jan G.E.,Szymański, Wiktor,Feringa, Ben L.,Janssen, Dick B.
experimental part, p. 7645 - 7650 (2012/09/21)
Six different bacterial haloalkane dehalogenases were recombinantly produced in Escherichia coli, purified, and used to catalyse the conversion of prochiral short-chain dihaloalkanes and a meso dihaloalkane, yielding enantioenriched haloalcohols. A two-reaction one-enzyme process was established in which the desymmetrisation of a dihaloalkane is followed by kinetic resolution of the chiral haloalcohol that is produced in the first step. In case of 1,3-dibromo-2-methylpropane and 1,3-dibromo-2-phenylpropane, an increase of the enantiomeric excess of the respective haloalcohol was observed in time, leading to ee values of >97%, with analytical yields of 24 and 52%, respectively. The results show that haloalkane dehalogenases can be used for the production of highly enantioenriched haloalcohols and that in some cases product enantiopurity can be improved by allowing a two-step one-enzyme tandem reaction.
