4469-66-3

Upstream product

• 591-50-4 iodobenzene 
• 40637-56-7 dimethyl allylmalonate 
• 54436-58-7 N-benzylpent-4-en-1-amine 
• 108-59-8 malonic acid dimethyl ester 
• 85291-68-5 (1,3-dibromopropan-2-yl)benzene 
• 4469-64-1 2-(2-phenyl-allyl)-malonic acid diethyl ester 
• 3360-54-1 3-bromo-2-phenylprop-1-ene 
• 3360-53-0 1-bromo-2-phenyl-1-propene 
• 105-53-3 diethyl malonate 
• 95124-07-5 dimethyl (prop-2-yn-1-yl)malonate 
• 98-80-6 phenylboronic acid 
• 18424-76-5 dimethyl malonate sodium salt 
• 74866-37-8 [3-(benzenesulfonyl)prop-1-en-2-yl]benzene 
• 186581-53-3 diazomethane 

Downstream Products

• 1392282-78-8 C₁₇H₂₄O₂ 
• 1392283-17-8 C₁₄H₁₈O₂ 
• 1392282-66-4 C₁₆H₁₈O₄ 
• 1392282-67-5 C₁₇H₂₂O₂ 
• 100747-48-6 dimethyl 3-phenylcyclopent-3-ene-1,1-dicarboxylate 
• 115340-08-4 dimethyl 3-phenylcyclopentane-1,1-dicarboxylate 
• 115463-41-7 dimethyl 3-phenylcyclohexane-1,1-dicarboxylate 
• 1392283-24-7 C₁₇H₂₀O₄ 
• 1392283-15-6 C₁₈H₂₂O₄ 
• 4469-65-2 2-(2-phenylallyl)malonic acid 
• 16433-43-5 4-phenyl-1-pentanoic acid 
• 4300-13-4 dimethyl 2-(2-phenylpropyl)malonate 

Relevant academic research and scientific papers

Desymmetrization of diolefinic diols by enantioselective amino-thiocarbamate-catalyzed bromoetherification: Synthesis of chiral spirocycles

A facile, efficient, and highly diastereo- and enantioselective bromoetherification of diolefinic diols has been developed using an amino-thiocarbamate catalyst. Further manipulations of the bromoether products enabled entry into a new class of spirocycle

Chiral hetero- and carbocyclic compounds from the asymmetric hydrogenation of cyclic alkenes

Several types of chiral hetero- and carbocyclic compounds have been synthesized by using the asymmetric hydrogenation of cyclic alkenes. N,P-Ligated iridium catalysts reduced six-membered cyclic alkenes with various substituents and heterofunctionality in good to excellent enantioselectivity, whereas the reduction of five-membered cyclic alkenes was generally less selective, giving modest enantiomeric excesses. The stereoselectivity of the hydrogenation depended more strongly on the substrate structure for the five- rather than the six-membered cyclic alkenes. The major enantiomer formed in the reduction of six-membered alkenes could be predicted from a selectivity model and isomeric alkenes had complementary enantioselectivity, giving opposite optical isomers upon hydrogenation. The utility of the reaction was demonstrated by using it as a key step in the preparation of chiral 1,3-cis-cyclohexane carboxylates. Copyright

Iridium-catalyzed hydroiodination of functionalized alkynes

The efficiency of an Ir(I)/HI system has been studied. The association of hydroiodic acid with iridium has been tested in the catalytic hydroiodination of alkynes. The use of [Ir(cod)Cl]2 dimer led to clean hydroiodination reactions and afforde

CYSTEINE PROTEASE INHIBITORS

The present invention is directed to compounds that are inhibitors of cysteine protease, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceut

NEW PALLADIUM MEDIATED CYCLOPENTANATION OF ALKANES BEARING A δ NUCLEOPHILIC SUBSTITUENT

A ?-alkylpalladium intermediate generated by carbopalladation of a double bond can be intramolecularly trapped by a β-diester or a β-keto ester enolate if a cyclopentane ring is formed.Otherwise, normal β-elimination is observed.