853005-07-9

Usage

Physical state

Colorless liquid

Odor

Slightly sweet

Uses

Solvent and intermediate in the production of pharmaceuticals, plastics, and agrochemicals; solvent in cleaning agents and coatings

Volatility

Low

Flammability

Not easily flammable

Safety

Relatively safe and stable to handle, but proper precautions should be taken when handling and storing.

Upstream product

• 96-49-1 [1,3]-dioxolan-2-one 
• 359-13-7 difluoroethanol 
• 540-51-2 2-bromoethanol 

Downstream Products

• 1118567-13-7 2-(2,2-difluoroethoxy)ethyl-4-methylbenzenesulfonate 

Relevant academic research and scientific papers

1,2-BIS(2,2-DIFLUOROETHOXY)ETHANE AND MANUFACTURING METHOD THEREOF

1,2-Bis(2,2-difluoroethoxy)ethane which can be used as electrolyte solution of a non-aqueous electrolyte secondary battery is provided. Used are 1,2-Bis(2,2-difluoroethoxy)ethane represented by the following formula (1): and a method for manufacturing 1,2-bis(2,2-difluoroethoxy)ethane including the step of reacting 2-(2,2-difluoroethoxy)ethanol represented by the following formula (2) with a compound represented by the general formula (3) in a basic compound or a basic compound-containing solvent: wherein Lg represents an anionic leaving group.

Glucopyranosyl derivative and application thereof in medicines

The invention relates to a glucopyranosyl derivative used as a sodium-dependent glucose transporter (SGLT) inhibitor, a medicinal composition containing the derivative, and an application of the derivative and the medicinal composition in medicines, and especially relates to the glucopyranosyl derivative represented by formula (I) or a pharmaceutically acceptable salt or all stereoisomers thereof, or the medicinal composition containing the derivative, and a use of the derivative and the medicinal composition in the preparation of medicines for treating diabetes and diabetes related diseases.

BENZYLBENZENE DERIVATIVES AND METHODS OF USE

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.

5,7-DIAMINOPYRAZOLO [4,3-d] PYRIMIDINES WITH PDE-5 INHIBITING ACTIVITY

This invention relates to compounds of formula (I).