85301-70-8Relevant academic research and scientific papers
Synthesis of 3-Alkylideneisoindolin-1-ones via Sonogashira Cyclocarbonylative Reactions of 2-Ethynylbenzamides
Albano, Gianluigi,Giuntini, Stefano,Aronica, Laura Antonella
supporting information, p. 10022 - 10034 (2020/09/03)
Cyclocarbonylative Sonogashira reactions of ortho-ethynylbenzamides have been investigated. The process is carried out under CO pressure, in the presence of a very small amount of PdCl2(PPh3)2 (0.4 mol %) as a catalytic precursor and without the need for
The Regiospecific Synthesis of N-Substituted Pyrazoles. I. 1- and 2-Substituted Indenopyrazol-4(1H)-ones
Lemke, Thomas L.,Sawhney, Kailash N.
, p. 1335 - 1340 (2007/10/02)
The reaction of enaminoketones (2 or 5) of 2-acyl-1,3-indandiones with unsymmetrical hydrazines results in the regiospecific synthesis of 1,3- or 2,3-disubstituted indenopyrazol-4(1H)-ones (4 or 7).The synthesis of the enaminoketones (2 or 5) is accomplished by way of amine addition to the 2-acyl-1,3-indandiones 8a-c or by reduction of the indenoisoxazole 9.The structural assignment of the isomeric indenopyrazoles 4 and 7 is based upon 1H-nmr chemical shifts.
