853055-71-7Relevant academic research and scientific papers
PYRIDIN-4-YLAMINE COMPOUNDS USEFUL IN THE TREATMENT OF NEUROPATHIC PAIN
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Page/Page column 30, (2010/02/11)
The present invention is directed to a method of use of triazolo-pyridazine compounds in the treatment of neuropathic pain. The present invention is also directed to the use of triazolo-pyridazine compounds in the treatment of psychiatric and mood disorde
N-Acridin-9-yl-butane-1,4-diamine derivatives: High-affinity ligands of the α2δ subunit of voltage gated calcium channels
Lim, Jongwon,Stock, Nicholas,Pracitto, Richard,Boueres, Julia K.,Munoz, Benito,Chaudhary, Ashok,Santini, Angelina M.,Orr, Karia,Schaffhauser, Herve,Bezverkov, Robert E.,Aiyar, Jayashree,Venkatraman, Shankar
, p. 1913 - 1916 (2007/10/03)
A series of N-acridin-9-yl-butane-1,4-diamines were found to be high-affinity ligands of the α2δ subunit of voltage gated calcium channels. The SAR studies of butane-1,4-diamine side chain resulted in the identification of compound 10 (IC5
