85310-69-6

Basic information

• Product Name: (R)-(+)-3-(hydroxymethyl)pyrrolidine
• CAS NO: 85310-69-6
• Molecular Weight: 101.148
• Mol File: 85310-69-6.mol
• Article Data: 23

Chemical Properties

• CAS DataBase Reference: (R)-(+)-3-(hydroxymethyl)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-3-(hydroxymethyl)pyrrolidine(85310-69-6)
• EPA Substance Registry System: (R)-(+)-3-(hydroxymethyl)pyrrolidine(85310-69-6)

Safety Data

• Hazardous Substances Data: 85310-69-6(Hazardous Substances Data)

Usage

General Description

(R)-(+)-3-(hydroxymethyl)pyrrolidine is a chiral compound that consists of a five-membered ring containing four carbon atoms and one nitrogen atom. It is an important building block in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. The hydroxymethyl group on the pyrrolidine ring allows for further modification and functionalization, making it a versatile intermediate in the synthesis of complex organic molecules. It is also used as a chiral auxiliary in asymmetric synthesis to control the stereochemistry of reactions. Due to its versatile nature and potential for use in a wide range of applications, (R)-(+)-3-(hydroxymethyl)pyrrolidine is a valuable chemical compound in the field of organic chemistry.

Upstream product

• 192214-04-3 (R)-1-Benzyl-3-benzyloxymethyl-pyrrolidine 
• 617-52-7 Dimethyl itakonate 
• 192214-01-0 Toluene-4-sulfonic acid (S)-5-oxo-tetrahydro-furan-3-ylmethyl ester 
• 96449-93-3 (R)-5-Oxo-1-((S)-1-phenyl-ethyl)-pyrrolidine-3-carboxylic acid 
• 138108-72-2 tert-butyl (R)-3-hydroxymethylpyrrolidine-1-carboxylate 
• 99735-45-2 methyl (3R)-1-<(R)-1-phenylethyl>-5-oxo-3-pyrrolidinecarboxylate 
• 915302-94-2 (3RS)-1-<(R)-1-phenylethyl>-5-oxo-3-pyrrolidinecarboxylic acid 
• 192214-03-2 (R)-1-Benzyl-4-benzyloxymethyl-pyrrolidin-2-one 
• 192214-02-1 β-azidomethyl γ-butyrolactone 
• 172796-28-0 (R)-4-((benzyloxy)methyl)dihydrofuran-2(3H)-one 
• 85701-08-2 (R)-4-(hydroxymethyl)dihydrofuran-2(3H)-one 
• 428518-36-9 methyl (R)-(-)-1-(phenylmethyl)-5-oxo-3-pyrrolidinecarboxylate 
• 51535-00-3 methyl 1-benzyl-5-oxo-3-pyrrolidinecarboxylate 
• 303111-43-5 (R)-(+)-1-(phenylmethyl)-3-hydroxymethylpyrrolidine 

Downstream Products

• 878013-26-4 (R)-[1-(4-bromophenyl)pyrrolidin-3-yl]methanol 
• 138108-72-2 tert-butyl (R)-3-hydroxymethylpyrrolidine-1-carboxylate 
• 1253574-98-9 (R)-(1-((5-(4-(bis(4-methoxybenzyl)amino)-6-methyl-1,3,5-triazin-2-yl)-6-(6-methoxypyridin-3-ylamino)pyridin-3-yl)methyl)pyrrolidin-3-yl)methanol 
• 1307881-21-5 (+/-)-N-carbobenzoxy-3-sulfamoyloxymethylpyrrolidine 
• 1307881-22-6 (+/-)-3-sulfamoyloxymethyl-N-(toluene-4-sulfonyl)pyrrolidine 
• 5731-17-9 1-(Phenylmethyl)-3-pyrrolidinemethanol 
• 1251297-15-0 C₁₂H₁₄N₂O 
• 192214-06-5 (R)-1-((benzyloxy)-carbonyl)pyrrolidine-3-carboxylic acid 
• 276872-88-9 (+/-)-3-[4-(4-flourophenylmethyl)piperidinomethyl]-pyrrolidine 
• 59379-02-1 tert-butyl 3-formylpyrrolidine-1-carboxylate 
• 479622-23-6 (2S,3R)-3-(1-{Benzyloxycarbonylamino-[(E)-benzyloxycarbonylimino]-methyl}-pyrrolidin-3-ylmethyl)-4-oxo-azetidine-2-carboxylic acid benzyl ester 

Relevant articles and documents

Discovery of phenylpyrrolidine derivatives as a novel class of retinol binding protein 4 (RBP4) reducers

Retinol-binding protein 4 (RBP4) is a potential drug target for metabolic and ophthalmologic diseases. A high-throughput screening of our compound library has identified a small-molecule RBP4 reducer 7a, as a hit compound. Aiming to provide a suitable too

Method for synthesizing N-Boc-3-pyrrolidine formaldehyde

The invention discloses a method for synthesizing N-Boc-3-pyrrolidine formaldehyde. The method comprises that dimethyl itaconate as a raw material undergoes an intramolecular cyclization reaction to produce methyl 5-oxo-3-pyrrolidine carboxylate, then the methyl 5-oxo-3-pyrrolidine carboxylate undergoes a reduction reaction to produce pyrrolidine-3-methanol, then the pyrrolidine-3-methanol is subjected to Boc protection so that N-Boc-pyrrolidine-3-methanol is obtained, and finally, the N-Boc-pyrrolidine-3-methanol is oxidized to form a final product compound. The method is simple and convenient, has a low cost, content greater than 99%, produces small environmental pollution and is suitable for industrial production.

AURORA KINASE COMPOUNDS AND METHODS OF THEIR USE

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