85344-72-5

Usage

Uses

Used in Pharmaceutical Research:
N-(2-methoxyphenyl)picolinamide is utilized as a reagent in pharmaceutical research for the development of new drug molecules. Its unique structure and reactivity make it a valuable component in the synthesis of potential therapeutic agents.
Used in Organic Synthesis:
In the field of organic synthesis, N-(2-methoxyphenyl)picolinamide serves as a key intermediate, facilitating the creation of various complex organic compounds for a range of applications.
Used in Agriculture:
N-(2-methoxyphenyl)picolinamide has potential applications in agriculture, possibly as a component in the development of agrochemicals or as a tool in the study of plant-pest interactions.
Used in Material Science:
Its unique chemical properties also lend N-(2-methoxyphenyl)picolinamide potential uses in material science, where it could contribute to the advancement of new materials with specific properties for various industries.

Upstream product

• 29745-44-6 pyridine-2-carbonyl chloride 
• 90-04-0 2-methoxy-phenylamine 
• 98-98-6 2-Picolinic acid 

Downstream Products

• 804484-48-8 N-(2,4-dimethoxyphenyl)picolinamide 

Relevant academic research and scientific papers

Enantioselective Synthesis of Atropisomeric Anilides via Pd(II)-Catalyzed Asymmetric C-H Olefination

Atropisomeric anilides have received tremendous attention as a novel class of chiral compounds possessing restricted rotation around an N-aryl chiral axis. However, in sharp contrast to the well-studied synthesis of biaryl atropisomers, the catalytic asym

Sulfonyl pyridine amide derivatives and preparation method thereof

The invention relates to a Sulfonyl pyridine amide derivatives and a preparation method thereof; the preparation method comprises the following steps: adding a compound as shown in a structural formula (II), a compound as shown in a structural formula (III), an oxidant, an additive and a heterogeneous biomass supported copper catalyst into a reaction container, adding a solvent, and carrying out astirring reaction at room temperature; and after the reaction is finished, filtering, extracting, concentrating, separating and purifying to obtain the sulfonyl pyridine amide derivative with the structural formula shown in the formula (I). The synthesis method of the sulfonyl pyridine amide derivatives is scientific and reasonable, and a series of sulfonyl pyridine amide derivatives are synthesized by a green and efficient synthesis method by adopting a heterogeneous biomass copper-loaded catalyst for catalytic reaction.

Copper-Catalyzed C-4 Carboxylation of 1-Naphthylamide Derivatives with CBr4/MeOH

A simple and practical copper catalyzed C-4 carboxylation reaction of 1-naphthylamide derivatives using carbon tetra bromide and methanol is reported here. Picolinamide and its derivatives are used as a bidentate directing group for the distal C4-H functi

Chelation-promoted Efficient C?H/N?H Cross Dehydrogenative Coupling between Picolinamides and Simple Ethers under Copper Catalysis

A highly efficient copper-catalyzed C?H/N?H cross dehydrogenative coupling between picolinamides and simple ethers was developed. The reaction was promoted by the chelation assistance of removable picolinyl group and exhibited excellent TON and TOF number. This method was applicable to both N-aryl and alkyl picolinamides as well as various cyclic and acyclic ethers with good functional group compatibility. It also possessed the merit of air and moisture tolerance and easy operation. (Figure presented.).

Proteomimetic compounds and methods

The present invention relates to compounds and pharmaceutical compositions which are proteomimetic and to methods for inhibiting the interaction of an alpha-helical protein with another protein or binding site. Methods for treating diseases or conditions which are modulated through interactions between alpha helical proteins and their binding sites are other aspects of the invention.

Comparative Mass Spectral Study of 2-Aza and 2'-Azabenzanilides and Their Thio Anlogues

Intramolecular aromatic substitution reactions involving nitrogen of the pyridine ring and sulfur have been observed in 2-aza- and 2'-azathiobenzanilides under electron impact while expelling the hydrogen or the ortho substituent from the molecular ions of these compounds.Hydrogen migration from nitrogen to the sulfur leads to the + ion while the migration of aryl group to sulfur affords +.Interesting ortho interactions of methoxy and the methyl substituents have also been noticed in 2-methoxy-2'-azathiobenzanilide and 2'-methyl-2-azathiobenzanilide in enhancing the relative abundance of +.But the mass spectra of the corresponding oxygen analogues contain peaks chiefly due to simple cleavages resulting in abundant benzoyl cations.