85365-61-3

Basic information

• Product Name: racemic 5(R)-1-aza-4(R)-carboxy-6(R)-hydroxy-4(R)-(phenylseleno)bicyclo<3.3.0>octane lactone
• CAS NO: 85365-61-3
• Molecular Weight: 308.239
• Mol File: 85365-61-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: racemic 5(R)-1-aza-4(R)-carboxy-6(R)-hydroxy-4(R)-(phenylseleno)bicyclo<3.3.0>octane lactone(CAS DataBase Reference)
• NIST Chemistry Reference: racemic 5(R)-1-aza-4(R)-carboxy-6(R)-hydroxy-4(R)-(phenylseleno)bicyclo<3.3.0>octane lactone(85365-61-3)
• EPA Substance Registry System: racemic 5(R)-1-aza-4(R)-carboxy-6(R)-hydroxy-4(R)-(phenylseleno)bicyclo<3.3.0>octane lactone(85365-61-3)

Safety Data

• Hazardous Substances Data: 85365-61-3(Hazardous Substances Data)

Upstream product

• 98675-05-9 (1R,7S,7aR)-7-Hydroxy-hexahydro-pyrrolizine-1-carboxylic acid methyl ester 
• 41646-10-0 2,3,5,6-Tetrahydro-1H-pyrrolizin-7-carbonsaeure-ethylester 
• 85365-57-7 ethyl (+/-)-1-hydroxy-2,3,5,6-tetrahydro-1H-pyrrolizine-7-carboxylate 
• 85365-60-2 1-Benzyl-1-aza-cyclooctan-5-on-4-carbonsaeureethylester 
• 98634-54-9 5(R)-1-aza-4-(1,3-dithian-2-ylidene)-6(S)-hydroxybicyclo<3.3.0>octane 
• 98634-55-0 racemic 5(R)-1-aza-4-(1,3-dithian-2-ylidene)bicyclo<3.3.0>octan-6-one 
• 85319-62-6 1-aza-4-(1,3-dithian-2-ylidene)-6(S)-(acetyloxy)bicyclo<3.3.0>octan-8-one 
• 5707-04-0 Phenylselenyl chloride 
• 140192-35-4 (1R,4R,S,5S)-4-(phenylseleno)-6-(2-pivaloyloxyethyl)-2-oxa-6-azabicyclo<3.3.0>octane-3-one 
• 107319-89-1 (3R)-3-(bromoacetoxy)-1-(2-pivaloyloxyethyl)pyrrolidine-2,5-dione 
• 107319-90-4 (1R)-6-(2-pivaloyloxyethyl)-2-oxa-6-azabicyclo<3.3.0>oct-4-ene-3,7-dione 
• 109755-70-6 (1S,5S)-2-oxa-6-aza-6-(2-(trimethylacetoxy)ethyl)-3-oxobicyclo<3.3.0>octane-7-thione 
• 107319-91-5 (1S,5S)-2-oxa-6-aza-6-(2-(trimethylacetoxy)ethyl)bicyclo<3.3.0>octane-3,7-dione 
• 107319-88-0 (3R)-3-acetoxy-1-(2-acetoxyethyl)pyrrolidine-2,5-dione 

Downstream Products

• 140385-63-3 (4R,5S,6R)-6-hydroxy-4-(hydroxymethyl)-4-(phenylseleno)-1-azabicyclo<3.3.0>octane 
• 130-01-8 (-)-integerrimine 
• 85365-59-9 1-(phenylseleno)platynecine 

Relevant articles and documents

Enantioselective Synthesis of Seven Pyrrolizidine Diols from a Single Precursor

The enantioselective synthesis of seven pyrrolizidine diols has been accomplished from a single, readily available intermediate.The key step of this general scheme involves an acetoxy-directed acyliminium ion-ketene dithioacetal cationic cyclization to gi

TOTAL SYNTHESIS OF OPTICALLY ACTIVE INTEGERRIMINE, A TWELVE-MEMBERED DILACTONIC PYRROLIZIDINE ALKALOID OF RETRONECINE TYPE. II. ENANTIOSELECTIVE SYNTHESIS OF (+)-RETRONECINE

For the total synthesis of optically active integerrimine, the twelve-membered dilactonic pyrrolizidine alkaloid, the necine base component (+)-retronecine has been synthesized enantioselectively.