853799-21-0

Basic information

• Product Name: methyl N-(1-acetylindolin-5-yl)-2-sulfamoyl benzoate
• Synonyms: methyl N-(1-acetylindolin-5-yl)-2-sulfamoyl benzoate
• CAS NO: 853799-21-0
• Molecular Weight: 374.417
• Mol File: 853799-21-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl N-(1-acetylindolin-5-yl)-2-sulfamoyl benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl N-(1-acetylindolin-5-yl)-2-sulfamoyl benzoate(853799-21-0)
• EPA Substance Registry System: methyl N-(1-acetylindolin-5-yl)-2-sulfamoyl benzoate(853799-21-0)

Safety Data

• Hazardous Substances Data: 853799-21-0(Hazardous Substances Data)

Upstream product

• 32692-19-6 5-nitro-2,3-dihydro-1H-indole 
• 4993-96-8 1-(5-aminoindolin-1-yl)ethanone 
• 26638-43-7 2-methoxycarbonylbenzenesulfonyl chloride 

Downstream Products

• 853799-23-2 N-(1-acetylindolin-5-yl)-N-methyl-2-sulfamoyl benzoic acid 
• 853799-22-1 methyl N-(1-acetylindolin-5-yl)-N-methyl-2-sulfamoyl benzoate 

Relevant articles and documents

Synthesis of substituted benzoindolinothiazepines using 5- And 6-nitroindolines

The synthesis of benzoindolothiazepine compounds was investigated using Friedel-Crafts reactions conditions from indolines. The amine function of indolinic identity was protected to avoid an alkylation of this function by methyl iodide. It was observed that the treatment of the desired amines with commercially available methyl chlorosulfanoylbenzonate resulted in the formation of sulfonamide compounds. It was also observed that the cyclization of the carboxylic acid under Friedel-Crafts conditions resulted in the formation of the desired tetracycles.