853995-05-8Relevant academic research and scientific papers
Synthesis of Chiral Cyclic Alcohols from Chiral Epoxides by H or N Substitution with Frontside Displacement
Da Silva Gomes, Roberto,Reddy, Karla Mahender,Corey
supporting information, p. 6310 - 6313 (2018/10/09)
Diverse examples are provided of enantioselective sequences for the transformation of cycloalkenes to either chiral trans-β-substituted cycloalkanols or chiral α-amino ketones.
Palladium-catalyzed diastereoselective coupling of propargylic oxiranes with terminal alkynes
Yoshida, Masahiro,Hayashi, Maiko,Shishido, Kozo
, p. 1643 - 1646 (2008/02/02)
A diastereoselective coupling of propargylic oxiranes with terminal alkynes has been developed with use of a palladium catalyst. The stereochemistries of the resulting 4-alkynyl-substituted 2,3-allenols have been altered depending on the palladium catalyst. An optically active antf-substituted aliene was synthesized from the reaction of an enantiomerically enriched propargylic oxirane without loss of chirality.
