854280-52-7

Upstream product

• 24852-71-9 2-[(phenylmethyl)thio]benzaldehyde 
• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 
• 4521-45-3 2-(phenylmethylthio)benzenemethanol 
• 58435-43-1 2-methoxycarbonyl-1-benzylthiobenzene 
• 100-39-0 benzyl bromide 
• 4892-02-8 Methyl thiosalicylate 
• 153511-19-4 S-(2-formylphenyl) N,N-dimethylthiocarbamate 
• 90-02-8 salicylaldehyde 

Downstream Products

• 1087009-21-9 2-(1,1-dioxo-2-phenyl-2,3-dihydro-1H-benzo[b]thiophen-3-yl)-N-hydroxyacetamide 
• 1087010-13-6 2-(1,1-dioxo-2-phenyl-2,3-dihydro-1H-benzo[b]thiophen-3-yl)acetic acid 
• 1087010-11-4 2-(1,1-dioxo-2-phenyl-2,3-dihydro-1H-benzo[b]thiophen-3-yl)acetic acid methyl ester 
• 1087010-09-0 (E)-3-(2-phenylmethanesulfonylphenyl)acrylic acid methyl ester 
• 854280-57-2 (E,E)-1-tert-butyldiphenylsilyloxy-3-(2-(3-(2-benzylsulfanylphenyl)prop-2-enylsulfanyl)phenyl)-2-propene 
• 854280-60-7 (E,E)-1-dimethoxymethyl-2-(3-(2-(3-(2-phenylmethylsulfanylphenyl)-2-propenylsulfanyl)phenyl)-2-propenylsulfanyl)benzene 
• 854280-58-3 (E,E)-3-(2-(3-(2-benzylsulfanylphenyl)-2-propenylsulfanyl)phenyl)-2-propenol 

Relevant academic research and scientific papers

BICYCLOSULFONYL ACID (BCSA) COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS

This invention pertains generally to the field of therapeutic compounds, and more particularly, to certain bicyclosulfonyl acid (BCSA) compounds which act as inhibitors of Tumour Necrosis Factor-α Converting Enzyme (TACE). The compounds are useful in the

Synthesis of substituted dihydrobenzothiopyrans and dihydrobenzopyrans by cation-mediated cyclisation reactions

Treatment with acid of thiosalicylaldehyde- and salicylaldehyde-derived phenyl 3-phenyl-2-propenyl thioethers and ethers possessing latent oxonium ion functionality triggers simple or tandem cyclisation to give substituted dihydrobenzothiopyrans and dihyd