854382-08-4 Usage
Nicotinonitrile family
A group of chemical compounds 2-[(pyridin-4-ylmethyl)amino]nicotinonitrile is a member of this family, sharing similar structural features and properties with other compounds in this group.
Pyridine ring
A six-membered aromatic ring with one nitrogen atom 2-[(pyridin-4-ylmethyl)amino]nicotinonitrile contains a pyridine ring, which is an important structural feature and contributes to its chemical reactivity and potential applications.
Amino group
-NH2 The presence of an amino group in the compound provides opportunities for further chemical reactions and modifications, making it a versatile building block for organic synthesis.
Nitrile functional group
-C≡N The nitrile group is another key structural feature of the compound, contributing to its reactivity and potential applications in various fields.
Organic synthesis
Building block for creating complex molecules 2-[(pyridin-4-ylmethyl)amino]nicotinonitrile is commonly used in organic synthesis as a starting material for the creation of more complex molecules.
Medicinal chemistry
Potential applications in pharmaceutical research and development Due to its structural features and potential biological activity, 2-[(pyridin-4-ylmethyl)amino]nicotinonitrile may be useful in the development of new drugs and therapies.
Agrochemicals
Potential use in the field of crop protection and pest control The versatile chemical properties and reactivity of 2-[(pyridin-4-ylmethyl)amino]nicotinonitrile may make it suitable for use in agrochemicals.
Materials science
Potential applications in the development of new materials The compound's unique properties and reactivity could be harnessed for the creation of new materials with specific functions or characteristics.
Check Digit Verification of cas no
The CAS Registry Mumber 854382-08-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,4,3,8 and 2 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 854382-08:
(8*8)+(7*5)+(6*4)+(5*3)+(4*8)+(3*2)+(2*0)+(1*8)=184
184 % 10 = 4
So 854382-08-4 is a valid CAS Registry Number.
854382-08-4Relevant academic research and scientific papers
Preparation method of apatinib
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Paragraph 0059; 0060, (2019/03/14)
The invention provides a preparation method of apatinib. The preparation method comprises that 2-halogenated-3-cyanopyridine as a raw material and 4-aminomethylpyridine undergo a substitution reactionto produce N-(pyridin-4-yl-methyl)-2-amino-3-cyanopyridine, the N-(pyridin-4-yl-methyl)-2-amino-3-cyanopyridine undergoes an esterification reaction to produce N-(pyridin-4-yl-methyl)-2-amino-3-picolinate, and the N-(pyridin-4-yl-methyl)-2-amino-3-picolinate and 1-(4-aminophenyl)cyclopentylformonitrile undergo an amidation reaction to produce apatinib (I). The preparation method has the advantages of low cost and easy availability of raw materials, simple processes, low cost, less waste water generation, safety and environmental protection, easy realization of reaction conditions, high reactivity and selectivity, few side reactions, few apatinib impurities, high purity and high yield.
