85448-22-2Relevant academic research and scientific papers
REGIOSPECIFIC α-HEXAFLUOROISOPROPYLIDENATION OF KETONES USING HEXAFLUOROACETONE
Ishihara, Takashi,Shinjo, Hiroshi,Inoue, Yoshihisa,Ando, Teiichi
, p. 1 - 20 (1983)
Hexafluoroacetone (HFA) reacted regiospecifically with various enol silyl ethers at -30 to -35 deg C in the presence of a Lewis acid to give HFA aldols, or α-bis(trifluoromethyl)hydroxymethyl carbonyl compounds, in good yields.The reaction of HFA with die
