85455-10-3

Upstream product

• 77794-06-0 7,7-bis(hydroxymethyl)-4,5α-epoxy-3-methoxy-17-methylmorphinan-6β-ol hydrochloride 
• 85455-00-1 7,7-bis<(tosyloxy)methyl>-4,5α-epoxy-3-methoxy-17-methylmorphinan-6-one 
• 77794-00-4 7,7-bis<(tosyloxy)methyl>-4,5α-epoxy-3-methoxy-17-methylmorphinan-6β-ol 
• 85455-01-2 7,7-bis<(tosyloxy)methyl>-4,5α-epoxy-3-methoxy-17-methylmorphinan-6α-ol 
• 85455-04-5 4,5α-epoxy-7β-(hydroxymethyl)-3-methoxy-17-methyl-6α,7α-(oxymethylene)morphinan 
• 85455-05-6 4,5α-epoxy-7β-formyl-3-methoxy-17-methyl-6α,7α-(oxymethylene)morphinan 
• 85455-03-4 7β-(acetoxymethyl)-4,5α-epoxy-3-methoxy-17-methyl-6α,7α-(oxymethylene)morphinan 
• 85455-07-8 4,5α-epoxy-3-methoxy-17-methyl-7β-(4-phenylbutyl)-6α,7α-(oxymethylene)morphinan 
• 85455-06-7 4,5α-epoxy-3-methoxy-17-methyl-7β-(4-phenyl-1,3-butadienyl)-6α,7α-(oxymethylene)morphinan 
• 85455-02-3 4,5α-epoxy-3-methoxy-17-methyl-7β-<(tosyloxy)methyl>-6β,7β-(oxymethylene)morphinan 
• 85455-11-4 7α,17-dimethyl-4,5α-epoxy-3-hydroxy-7β-(4-phenylbutyl)morphinan-6-one 
• 85455-09-0 7α,17-dimethyl-4,5α-epoxy-3-methoxy-7β-(4-phenylbutyl)morphinan-6α-ol 

Relevant academic research and scientific papers

7β-Arylalkyl-7α-methyl-6-oxo or 6α-hydroxy-3-methoxy or 3-hydroxy-4,5α-epoxy-17-methyl or 17-cycloalkyl-methylmorphinans

Disclosed are 7β-arylalkyl-7α-methyl-6-oxo or 6α-hydroxy-3-methoxy or 3-hydroxy-4,5α-epoxy-17-methyl or 17-cycloalkylmethyl-morphinans of the formula: STR1 wherein R is H or methyl, X is oxo or α-hydroxy, n is 2 to 4 and R1 is methyl, cycloprop

7&α- or 7&β-(4-Phenylbutyl)dihydrocodeine Derivatives

A lipophilic 4-phenylbutyl group was selectively incorporated into the 7α- or 7β-position of the morphine nucleus by use of 6,7-oxymethylene (oxetane) intermediates. 7,7-Bisdihydroisocodeine (2) with dilute NaOH gave 6β,7β-(oxymethylene)